Autism spectrum disorders comprise a range of neurodevelopmental disorders characterized
by deficits in social interaction and communication, and by repetitive behaviour 1 . …

Endocannabinoids (eCBs) exert major control over neuronal activity by activating cannabinoid
receptors (CBRs). The functionality of the eCB system is primarily ascribed to the well-…

Escaping from imminent danger is an instinctive behaviour that is fundamental for survival,
and requires the classification of sensory stimuli as harmless or threatening. The absence of …

When faced with potential predators, animals instinctively decide whether there is a threat
they should escape from, and also when, how, and where to take evasive action. While …

Animals can choose to act upon, or to ignore, sensory stimuli, depending on circumstance
and prior knowledge. This flexibility is thought to depend on neural inhibition, through …

When faced with predatory threats, escape towards shelter is an adaptive action that offers
long-term protection against the attacker. Animals rely on knowledge of safe locations in the …

Endogenous cannabinoids are diffusible lipid ligands of the main cannabinoid receptors
type 1 and 2 (CB 1 R and CB 2 R). In the central nervous system endocannabinoids are …

Neuroligins are postsynaptic cell adhesion molecules that associate with presynaptic
neurexins. Both factors form a transsynaptic connection, mediate signaling across the synapse, …

When faced with predatorial threats, escape towards shelter is an adaptive action that offers
long-term protection against the attacker. From crustaceans to mammals, animals rely on …

Midbrain raphe nuclei provide strong serotonergic projections to the hippocampus, in which
serotonin (5-HT) exerts differential effects mediated by multiple 5-HT receptor subtypes. The …