Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to
raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a …

Mutations in IDH induce epigenetic and transcriptional reprogramming, differentiation bias,
and susceptibility to mitochondrial inhibitors in cancer cells. Here, we first show that cell lines, …

Chromatin organization is essential for appropriate interpretation of the genetic information.
Here, we demonstrated that the chromatin-associated proteins HP1 are dispensable for …

Skeletal muscle is a plastic tissue that adapts to exercise through fusion of muscle stem
cells (MuSCs) with myofibers, a physiological process referred to as myonuclear accretion. …

Isocitrate dehydrogenases (IDH) are involved in redox control and central metabolism. Mutations
in IDH induce epigenetic and transcriptional reprogramming, differentiation bias, BCL-2 …

Cancer cachexia (CC) is a multifactorial syndrome in patients with cancer that leads to
unintentional body weight loss mainly caused by loss of skeletal muscle tissue (ie, muscle atrophy…

1 Combinatory therapy targeting mitochondrial oxidative phosphorylation improves 1 efficacy of
IDH mutant inhibitors in acute my Page 1 1 Combinatory therapy targeting mitochondrial …

Heterochromatin formation has been proposed to involve phase transitions on the level of
the three-dimensional folding of heterochromatin regions and the liquid–liquid demixing of …

Post‐injury skeletal muscle regeneration requires interactions between myogenic and non‐myogenic
cells. Our knowledge on the regeneration process is mainly based on models …

Lipid mediators are a class of signaling molecules that play important roles in various
physiological processes, including inflammation, blood pressure regulation, and energy …