User profiles for A.F Ajayi

Ayodeji Ajayi

Reader, Ladoke Akintola University of T
Verified email at lautech.edu.ng
Cited by 1575

[HTML][HTML] Staging of the estrous cycle and induction of estrus in experimental rodents: an update

AF Ajayi, RE Akhigbe - Fertility research and practice, 2020 - Springer
Background Determination of the phases of the estrous cycle and induction of estrus (heat)
in experimental animals remains useful, especially in reproductive function research. Main …

The physiology of male reproduction: Impact of drugs and their abuse on male fertility

AF Ajayi, RE Akhigbe - Andrologia, 2020 - Wiley Online Library
Male factor accounts for about 30–50% of infertility. A common cause of male infertility is
drug abuse; either illicit or prolonged use of prescribed drugs. This study provides a review of …

[HTML][HTML] Viral infections and male infertility: a comprehensive review of the role of oxidative stress

RE Akhigbe, S Dutta, MA Hamed, AF Ajayi… - … in Reproductive Health, 2022 - frontiersin.org
Viral infections have been a part of human existence to date, though viruses have posed a
huge threat with various outbreaks lately. These threats are associated with reproductive …

[HTML][HTML] Omega-3 fatty acid rescues ischaemia/perfusion-induced testicular and sperm damage via modulation of lactate transport and xanthine oxidase/uric acid …

…, MA Hamed, AF Odetayo, TM Akhigbe, AF Ajayi… - Biomedicine & …, 2021 - Elsevier
This study aimed to explore the potential antioxidant, anti-inflammatory, and anti-apoptotic
effects of omega 3 fatty acid (Ω-3) in a rat model of testicular torsion/detorsion (T/D). Under …

[HTML][HTML] Glutamine restores testicular glutathione-dependent antioxidant defense and upregulates NO/cGMP signaling in sleep deprivation-induced reproductive …

…, GO Tajudeen, MM Titiloye, NF Ayinla, AF Ajayi - Biomedicine & …, 2022 - Elsevier
Oxidative stress has been linked with sleep deprivation (SD)-induced pathological conditions
and reproductive dysfunction. On the other hand, glutamine has been established to have …

[PDF][PDF] In vivo exposure to codeine induces reproductive toxicity: role of HER2 and p53/Bcl-2 signaling pathway

AF Ajayi, RE Akhigbe - Heliyon, 2020 - cell.com
Several studies have implicated codeine use in the aetiopathogenesis of male infertility.
The purpose of this study was to investigate the role of HER2, Ki67, oestrogen and p53/Bcl-2 …

Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis

AF Ajayi, RE Akhigbe - Redox Report, 2020 - Taylor & Francis
Background: Opioids have been implicated to induce infertility. Although codeine remains
the most used opioid for recreational purpose, no study has documented its effect on sperm …

Laboratory diagnosis of COVID-19 in Africa: availability, challenges and implications

EK Oladipo, AF Ajayi, AN Odeyemi… - Drug Discoveries & …, 2020 - jstage.jst.go.jp
The COVID-19 infection has been a matter of urgency to tackle around the world today, there
exist 200 countries around the world and 54 countries in Africa that the COVID-19 infection …

Impact of hypoxia on male reproductive functions

…, RE Akhigbe, LO Ajayi, AF Ajayi - Molecular and Cellular …, 2023 - Springer
Male reproductive functions, which include testicular steroidogenesis, spermatogenesis, and
sexual/erectile functions are key in male fertility, but may be adversely altered by several …

Codeine-induced hepatic injury is via oxido-inflammatory damage and caspase-3-mediated apoptosis

…, AA Adelakun, OS Olorunnisola, AF Ajayi - Molecular Biology …, 2020 - Springer
Codeine (3-methylmorphine) is a known analgesic, antitussive, and antidiarrheal drug that
is often abused for recreational purposes. It is metabolized in the liver via the cytochrome …