Organ-specific functions of tissue-resident macrophages in the steady-state heart are
unknown. Here, we show that cardiac macrophages facilitate electrical conduction through the …

Objectives : The aim of this study was to characterize the morphological features of plaque
erosion and calcified nodule in patients with acute coronary syndrome (ACS) by optical …

Interferon regulatory factor 3 (IRF3) and type I interferons (IFNs) protect against infections 1
and cancer 2 , but excessive IRF3 activation and type I IFN production cause …

Importance Coronavirus disease 2019 (COVID-19) is an acute respiratory illness with a
high rate of hospitalization and mortality. Biomarkers are urgently needed for patient risk …

Since optical coherence tomography (OCT) was first performed in humans two decades ago,
this imaging modality has been widely adopted in research on coronary atherosclerosis …

Background : Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However,
its clinical significance in coronary arteries has never been systematically investigated. …

Ultrahigh resolution two and three-dimensional optical coherence tomography (OCT)
imaging was performed using a miniaturized, two-axis scanning catheter based upon …

Tissue macrophage numbers vary during health versus disease. Abundant inflammatory
macrophages destruct tissues, leading to atherosclerosis, myocardial infarction and heart failure…

Inflammation is the physiologic reaction to cellular and tissue damage caused by trauma,
ischemia, infection, and other pathologic conditions. Elevation of white blood cell count (WBC) …

Sudden cardiac death, arising from abnormal electrical conduction, occurs frequently in
patients with coronary heart disease. Myocardial ischemia simultaneously induces arrhythmia …