User profiles for Aaron F. Alexander-Bloch
Aaron F Alexander-BlochUniversity of Pennsylvania and Children's Hospital of Philadelphia Verified email at post.harvard.edu Cited by 8549 |
[HTML][HTML] Disrupted modularity and local connectivity of brain functional networks in childhood-onset schizophrenia
AF Alexander-Bloch, N Gogtay, D Meunier… - Frontiers in systems …, 2010 - frontiersin.org
Modularity is a fundamental concept in systems neuroscience, referring to the formation of
local cliques or modules of densely intra-connected nodes that are sparsely inter-connected …
local cliques or modules of densely intra-connected nodes that are sparsely inter-connected …
On testing for spatial correspondence between maps of human brain structure and function
A critical issue in many neuroimaging studies is the comparison between brain maps.
Nonetheless, it remains unclear how one should test hypotheses focused on the overlap or spatial …
Nonetheless, it remains unclear how one should test hypotheses focused on the overlap or spatial …
Simple models of human brain functional networks
PE Vértes, AF Alexander-Bloch… - Proceedings of the …, 2012 - National Acad Sciences
Human brain functional networks are embedded in anatomical space and have topological
properties—small-worldness, modularity, fat-tailed degree distributions—that are …
properties—small-worldness, modularity, fat-tailed degree distributions—that are …
The anatomical distance of functional connections predicts brain network topology in health and schizophrenia
AF Alexander-Bloch, PE Vértes, R Stidd… - Cerebral …, 2013 - academic.oup.com
The human brain is a topologically complex network embedded in anatomical space. Here,
we systematically explored relationships between functional connectivity, complex network …
we systematically explored relationships between functional connectivity, complex network …
Development of structure–function coupling in human brain networks during youth
…, DJ Oathes, AF Alexander-Bloch… - Proceedings of the …, 2020 - National Acad Sciences
The protracted development of structural and functional brain connectivity within distributed
association networks coincides with improvements in higher-order cognitive processes such …
association networks coincides with improvements in higher-order cognitive processes such …
Impaired long distance functional connectivity and weighted network architecture in Alzheimer's disease
…, X Zhang, J Liu, Y Duan, AF Alexander-Bloch… - Cerebral …, 2014 - academic.oup.com
Alzheimer's disease (AD) is increasingly recognized as a disconnection syndrome, which
leads to cognitive impairment due to the disruption of functional activity across large networks …
leads to cognitive impairment due to the disruption of functional activity across large networks …
[HTML][HTML] Obesity associated with increased brain age from midlife
L Ronan, AF Alexander-Bloch, K Wagstyl, S Farooqi… - Neurobiology of …, 2016 - Elsevier
Common mechanisms in aging and obesity are hypothesized to increase susceptibility to
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …
Intrinsic activity development unfolds along a sensorimotor–association cortical axis in youth
Animal studies of neurodevelopment have shown that recordings of intrinsic cortical activity
evolve from synchronized and high amplitude to sparse and low amplitude as plasticity …
evolve from synchronized and high amplitude to sparse and low amplitude as plasticity …
[PDF][PDF] Individual variation in functional topography of association networks in youth
The spatial distribution of large-scale functional networks on the cerebral cortex differs
between individuals and is particularly variable in association networks that are responsible for …
between individuals and is particularly variable in association networks that are responsible for …
Sex-chromosome dosage effects on gene expression in humans
…, LS Clasen, AF Alexander-Bloch… - Proceedings of the …, 2018 - National Acad Sciences
A fundamental question in the biology of sex differences has eluded direct study in humans:
How does sex-chromosome dosage (SCD) shape genome function? To address this, we …
How does sex-chromosome dosage (SCD) shape genome function? To address this, we …