SARS-CoV-2 mRNA vaccination induces robust humoral and cellular immunity in the
circulation; however, it is currently unknown whether it elicits effective immune responses in the …

Total hip arthroplasty is a cost-effective surgical procedure undertaken to relieve pain and
restore function to the arthritic hip joint. More than 1 million arthroplasties are done every year …

Chimeric antigen receptor T (CAR-T) cell therapy is a new pillar in cancer therapeutics;
however, its application is limited by the associated toxicities. These include cytokine release …

Multiple Sclerosis (MS) is a complex disease with an unknown etiology and no effective cure,
despite decades of extensive research that led to the development of several partially …

Treatment of advanced, poorly immunogenic tumors in animal models, considered the closest
simulation available thus far for conditions observed in cancer patients, remains a major …

Despite the widespread use of vaccinia virus (VV) as a vector for other Ags and as the
smallpox vaccine, there is little information available about the protective components of the …

Tumour cell phagocytosis by antigen presenting cells (APCs) is critical to the generation of
antitumour immunity. However, cancer cells can evade phagocytosis by upregulating anti-…

The purpose of this study was to measure the impact of periprosthetic joint infections (PJIs)
on the length of hospitalization, readmissions, and the associated costs. Between 2007 and …

Cellular senescence is a plausible mediator of inflammation-related tissue dysfunction. In
the aged brain, senescent cell identities and the mechanisms by which they exert adverse …

Blood-brain barrier (BBB) breakdown and immune cell infiltration into the central nervous
system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8 + T cells …