Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination
SARS-CoV-2 mRNA vaccination induces robust humoral and cellular immunity in the
circulation; however, it is currently unknown whether it elicits effective immune responses in the …
circulation; however, it is currently unknown whether it elicits effective immune responses in the …
Hip arthroplasty
R Pivec, AJ Johnson, SC Mears, MA Mont - The Lancet, 2012 - thelancet.com
Total hip arthroplasty is a cost-effective surgical procedure undertaken to relieve pain and
restore function to the arthritic hip joint. More than 1 million arthroplasties are done every year …
restore function to the arthritic hip joint. More than 1 million arthroplasties are done every year …
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts
…, KE Hedin, NE Kay, AJ Johnson… - Blood, The Journal …, 2019 - ashpublications.org
Chimeric antigen receptor T (CAR-T) cell therapy is a new pillar in cancer therapeutics;
however, its application is limited by the associated toxicities. These include cytokine release …
however, its application is limited by the associated toxicities. These include cytokine release …
The relevance of animal models in multiple sclerosis research
Multiple Sclerosis (MS) is a complex disease with an unknown etiology and no effective cure,
despite decades of extensive research that led to the development of several partially …
despite decades of extensive research that led to the development of several partially …
[HTML][HTML] Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
Treatment of advanced, poorly immunogenic tumors in animal models, considered the closest
simulation available thus far for conditions observed in cancer patients, remains a major …
simulation available thus far for conditions observed in cancer patients, remains a major …
Cellular and humoral immunity against vaccinia virus infection of mice
R Xu, AJ Johnson, D Liggitt, MJ Bevan - The Journal of Immunology, 2004 - journals.aai.org
Despite the widespread use of vaccinia virus (VV) as a vector for other Ags and as the
smallpox vaccine, there is little information available about the protective components of the …
smallpox vaccine, there is little information available about the protective components of the …
[HTML][HTML] Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity
Tumour cell phagocytosis by antigen presenting cells (APCs) is critical to the generation of
antitumour immunity. However, cancer cells can evade phagocytosis by upregulating anti-…
antitumour immunity. However, cancer cells can evade phagocytosis by upregulating anti-…
The economic impact of periprosthetic infections following total knee arthroplasty at a specialized tertiary-care center
BH Kapadia, MJ McElroy, K Issa, AJ Johnson… - The Journal of …, 2014 - Elsevier
The purpose of this study was to measure the impact of periprosthetic joint infections (PJIs)
on the length of hospitalization, readmissions, and the associated costs. Between 2007 and …
on the length of hospitalization, readmissions, and the associated costs. Between 2007 and …
[HTML][HTML] Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance
…, JM Kachergus, TA White, RK Johnson… - Nature …, 2022 - nature.com
Cellular senescence is a plausible mediator of inflammation-related tissue dysfunction. In
the aged brain, senescent cell identities and the mechanisms by which they exert adverse …
the aged brain, senescent cell identities and the mechanisms by which they exert adverse …
[HTML][HTML] Antigen recognition detains CD8+ T cells at the blood-brain barrier and contributes to its breakdown
Blood-brain barrier (BBB) breakdown and immune cell infiltration into the central nervous
system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8 + T cells …
system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8 + T cells …