[HTML][HTML] Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease

YR Lewis-Israeli, AH Wasserman, MA Gabalski… - Nature …, 2021 - nature.com
Congenital heart defects constitute the most common human birth defect, however
understanding of how these disorders originate is limited by our ability to model the human heart …

Thermal decomposition of ferulic acid

W Fiddler, WE Parker, AE Wasserman… - Journal of agricultural …, 1967 - ACS Publications
The thermal decomposition of ferulic acid has been studied by thermal gravimetric analysis.
The decomposition products were separated by gas-liquid chromatography and identified by …

Neuronal atrophy early in degenerative ataxia is a compensatory mechanism to regulate membrane excitability

JM Dell'Orco, AH Wasserman, R Chopra… - Journal of …, 2015 - Soc Neuroscience
Neuronal atrophy in neurodegenerative diseases is commonly viewed as an early event in
a continuum that ultimately results in neuronal loss. In a mouse model of the polyglutamine …

Thermally produced flavor components in the aroma of meat and poultry

AE Wasserman - Journal of Agricultural and Food Chemistry, 1972 - ACS Publications
The desirable flavor of meat is developed by the applica-tion of heat. Raw meat in general
has a salty, metallic, bloody taste and a sweet aroma resembling serum. Raw pork mayalso …

Inhibition of lactic acid bacteria by herbs

…, JC Kissinger, AE Wasserman - Journal of Food …, 1983 - Wiley Online Library
Increasing concentrations (0.5–8g/liter) of oregano, rosemary, sage, and thyme progressively
delayed growth and acid production by Lactobacillus plantarum and Pediococcus …

[HTML][HTML] Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy

…, S Friedline, M Wauchope, A Arora, AH Wasserman… - JCI insight, 2020 - ncbi.nlm.nih.gov
Mutations in cardiac myosin binding protein C (MyBP-C, encoded by MYBPC3) are the most
common cause of hypertrophic cardiomyopathy (HCM). Most MYBPC3 mutations result in …

[HTML][HTML] A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization

…, C O'Hern, P Muniyandi, A Wasserman… - Nature …, 2023 - nature.com
Pluripotent stem cell-derived organoids can recapitulate significant features of organ
development in vitro. We hypothesized that creating human heart organoids by mimicking aspects …

Formation of N-nitrosodimethylamine from naturally occurring quaternary ammonium compounds and tertiary amines

W Fiddler, JW Pensabene, RC Doerr, AE Wasserman - Nature, 1972 - nature.com
THE potential for the formation of N-nitrosamines in the human environment, either during
the processing of foods or in vivo from nitrate and/or nitrite, and precursor amines has …

Organoleptic evaluation of three phenols present in wood smoke

AE WASSERMAN - Journal of Food Science, 1966 - Wiley Online Library
Guaiacol, 4‐methyl guaiacol, and 2,6‐di–methoxyphenol, components of wood smoke
condensates, were evaluated organoleptically. Mean panel thresholds of the taste and odor in …

[HTML][HTML] Heart organoids and engineered heart tissues: Novel tools for modeling human cardiac biology and disease

YR Lewis-Israeli, AH Wasserman, A Aguirre - Biomolecules, 2021 - mdpi.com
Organoids are three-dimensional in vitro cell constructs that recapitulate organ properties
and structure to a significant extent. They constitute particularly useful models to study …