Combinatorial prediction of marker panels from single‐cell transcriptomic data

…, A Schnell, LV Cammarata, A YaoSmith… - Molecular systems …, 2019 - embopress.org
Single‐cell transcriptomic studies are identifying novel cell populations with exciting functional
roles in various in vivo contexts, but identification of succinct gene marker panels for such …

[PDF][PDF] Combinatorial prediction of gene-marker panels from single-cell transcriptomic data

C Delaney, A Schnell, LV Cammarata, A Yao-Smith… - scholar.archive.org
Single-cell transcriptomic studies are identifying novel cell populations with exciting functional
roles in various in vivo contexts, but identification of succinct gene-marker panels for such …

Combinatorial prediction of marker panels from single‐cell transcriptomic data

A Regev, VK Kuchroo, M Singer - 2019 - dspace.mit.edu
Single-cell transcriptomic studies are identifying novel cell populations with exciting functional
roles in various in vivo contexts, but identification of succinct gene marker panels for such …

Subcellular location of source proteins improves prediction of neoantigens for immunotherapy

A Castro, S Kaabinejadian, H Yari, W Hildebrand… - The EMBO …, 2022 - embopress.org
Antigen presentation via the major histocompatibility complex (MHC) is essential for anti‐tumor
immunity. However, the rules that determine which tumor‐derived peptides will be …

A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X

Z Jowhar, A Xu, S Venkataramanan… - Molecular Systems …, 2024 - embopress.org
The road from transcription to protein synthesis is paved with many obstacles, allowing for
several modes of post-transcriptional regulation of gene expression. A fundamental player in …

Algorithms for a Commons Cell Atlas

AS Booeshaghi, Á Gálvez-Merchán, L Pachter - bioRxiv, 2024 - biorxiv.org
Cell atlas projects curate representative datasets, cell types, and marker genes for tissues
across an organism. Despite their ubiquity, atlas projects rely on duplicated and manual effort …

Systems level identification of a matrisome-associated macrophage polarisation state in multi-organ fibrosis

JF Ouyang, K Mishra, Y Xie, H Park, KY Huang… - Elife, 2023 - elifesciences.org
Tissue fibrosis affects multiple organs and involves a master-regulatory role of macrophages
which respond to an initial inflammatory insult common in all forms of fibrosis. The recently …

CellCover Defines Conserved Cell Types and Temporal Progression in scRNA-seq Data across Mammalian Neocortical Development

L Ji, A Wang, S Sonthalia, DQ Naiman, L Younes… - bioRxiv, 2023 - biorxiv.org
Accurate identification of cell classes across the tissues of living organisms is central in the
analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across …

Single-cell analysis for whole-organism datasets

AO Pisco, B Tojo, A McGeever - Annual Review of Biomedical …, 2021 - annualreviews.org
Cell atlases are essential companions to the genome as they elucidate how genes are used
in a cell type–specific manner or how the usage of genes changes over the lifetime of an …

Detection of subpopulation-specific neuronal membrane molecules using single-cell expression data

M Zátko - 2023 - dspace.cuni.cz
Single-cell RNA sequencing is a powerful technology that allows the investigation of gene
expression at an unprecedented level. Insights into gene expression in individual cells can …