User profiles for Aashil A. Batavia

Aashil A. Batavia

Novartis, SIB
Verified email at novartis.com
Cited by 177

Clear cell renal cell carcinoma with wild‐type von Hippel‐Lindau gene: a non‐existent or new tumour entity?

AA Batavia, P Schraml, H Moch - Histopathology, 2019 - Wiley Online Library
The current World Health Organisation ( WHO ) classification of renal tumours is based on
characteristic histological features or specific molecular alterations. von Hippel‐Lindau ( VHL ) …

[HTML][HTML] Biallelic ELOC-inactivated renal cell carcinoma: molecular features supporting classification as a distinct entity

AA Batavia, D Rutishauser, B Sobottka, P Schraml… - Modern Pathology, 2023 - Elsevier
Approximately 70% of clear cell renal cell carcinoma (ccRCC) is characterized by the biallelic
inactivation of von Hippel-Lindau (VHL) on chromosome 3p. ELOC-mutated (Elongin C-…

[HTML][HTML] The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions

Z Fan, R Ardicoglu, AA Batavia, R Rust, L von Ziegler… - Angiogenesis, 2023 - Springer
The molecular mechanisms of angiogenesis have been intensely studied, but many genes
that control endothelial behavior and fate still need to be described. Here, we characterize …

[HTML][HTML] Classic chromophobe renal cell carcinoma incur a larger number of chromosomal losses than seen in the eosinophilic subtype

R Ohashi, P Schraml, S Angori, AA Batavia, NJ Rupp… - Cancers, 2019 - mdpi.com
Chromophobe renal cell carcinoma (chRCC) is a renal tumor subtype with a good prognosis,
characterized by multiple chromosomal copy number variations (CNV). The World Health …

[HTML][HTML] Loss of CDKN1A mRNA and protein expression are independent predictors of poor outcome in chromophobe renal cell carcinoma patients

R Ohashi, S Angori, AA Batavia, NJ Rupp, Y Ajioka… - Cancers, 2020 - mdpi.com
Chromophobe renal cell carcinoma (chRCC) patients have good prognosis. Only 5%–10%
patients die of metastatic disease after tumorectomy, but tumor progression cannot be …

Within-patient genetic diversity of SARS-CoV-2

J Kuipers, AA Batavia, KP Jablonski, F Bayer… - BioRxiv, 2020 - biorxiv.org
SARS-CoV-2, the virus responsible for the current COVID-19 pandemic, is evolving into
different genetic variants by accumulating mutations as it spreads globally. In addition to this …

[HTML][HTML] Impact of differing methodologies for serum miRNA-371a-3p assessment in stage I testicular germ cell cancer recurrence

…, C Rothermundt, R Cathomas, AA Batavia… - Frontiers in …, 2022 - frontiersin.org
Current evidence shows that serum miR-371a-3p can identify disease recurrence in testicular
germ cell tumour (TGCT) patients and correlates with tumour load. Despite convincing …

[HTML][HTML] Spatial distribution of private gene mutations in clear cell renal cell carcinoma

AL Moore, AA Batavia, J Kuipers, J Singer, E Burcklen… - Cancers, 2021 - mdpi.com
Simple Summary Tumours consist of multiple groups of similar cells resulting from differing
evolutionary trajectories, ie, subclones. These subclones are prevalent in clear cell renal cell …

[HTML][HTML] Next Generation Sequencing of Reactive Stroma and Residual Breast Cancer Cells in Tumor Bed after Neoadjuvant Chemotherapy

…, A Christiansen, M Lukamowicz-Rajska, AA Batavia… - Cancers, 2022 - mdpi.com
Simple Summary Primary systemic or neoadjuvant chemotherapy of breast cancer has become
a standard therapy option in locally advanced or triple negative or Her2 positive breast …

[HTML][HTML] Prognostic immune cell profiling of malignant pleural effusion patients by computerized immunohistochemical and transcriptional analysis

C Wu, F Mairinger, R Casanova, AA Batavia… - Cancers, 2019 - mdpi.com
Malignant pleural effusion (MPE) is a severe condition of advanced tumors without effective
therapy. We used digitalized immunohistochemical and transcriptional approaches to …