[HTML][HTML] FTD/ALS-associated poly (GR) protein impairs the Notch pathway and is recruited by poly (GA) into cytoplasmic inclusions
C9ORF72 repeat expansion is the most common genetic mutation in frontotemporal dementia
(FTD) and amyotrophic lateral sclerosis (ALS). Abnormal dipeptide repeat proteins (DPRs) …
(FTD) and amyotrophic lateral sclerosis (ALS). Abnormal dipeptide repeat proteins (DPRs) …
[HTML][HTML] CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro
KE Meijboom, A Abdallah, NP Fordham… - Nature …, 2022 - nature.com
A GGGGCC 24+ hexanucleotide repeat expansion (HRE) in the C9ORF72 gene is the most
common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (…
common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (…
[HTML][HTML] Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD
…, W Liu, MJ Rybin, G Gaidosh, A Abdallah… - Molecular …, 2020 - Springer
Background The C9ORF72 hexanucleotide repeat expansion is the most common known
genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two …
genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two …
Artificial microRNA suppresses C9ORF72 variants and decreases toxic dipeptide repeat proteins in vivo
GT Cabrera, KE Meijboom, A Abdallah, H Tran… - Gene Therapy, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects motor
neurons, causing progressive muscle weakness and respiratory failure. The presence of an …
neurons, causing progressive muscle weakness and respiratory failure. The presence of an …
User experience design using machine learning: a systematic review
User experience (UX) is the key to increased productivity by enhancing the usability and
interactivity of the product. Machine learning (ML) solutions have raised user and academic …
interactivity of the product. Machine learning (ML) solutions have raised user and academic …
comparative analysis of green ict practices among palestinian and malaysian in sme food enterprises during covid-19 pandemic
M Mustafa, A Abbas - PalArch's Journal of Archaeology of Egypt …, 2021 - archives.palarch.nl
Covid-19 requires the demand to spread awareness among people about the adverse
environmental impact of operations done in industries in order to sustain the environment. For …
environmental impact of operations done in industries in order to sustain the environment. For …
Automated deep learning in ophthalmology: AI that can build AI
C O'Byrne, A Abbas, E Korot… - Current Opinion in …, 2021 - journals.lww.com
Automated deep learning allows users without coding expertise to develop deep learning
algorithms. It is rapidly establishing itself as a valuable tool for those with limited technical …
algorithms. It is rapidly establishing itself as a valuable tool for those with limited technical …
[HTML][HTML] Evaluating an automated machine learning model that predicts visual acuity outcomes in patients with neovascular age-related macular degeneration
A Abbas, C O'Byrne, DJ Fu, G Moraes… - Graefe's Archive for …, 2022 - Springer
Purpose Neovascular age-related macular degeneration (nAMD) is a major global cause of
blindness. Whilst anti-vascular endothelial growth factor (anti-VEGF) treatment is effective, …
blindness. Whilst anti-vascular endothelial growth factor (anti-VEGF) treatment is effective, …
[PDF][PDF] Smart irrigation system based on the internet of things and the cloud
A water system is a technique for giving water to plants to grow and create. Water in plants
or water systems is not a cutting-edge idea; it has been followed and applied from one …
or water systems is not a cutting-edge idea; it has been followed and applied from one …
Polymer Composite @ Nano TiO2/LiBF4 as an Electrospun Fiber Nano Composite Electrolyte: Preparation, Characterization and Electrical Properties
…, MN Elsabagh, SL Abdelaziz, AM Abbas - Journal of Inorganic and …, 2023 - Springer
As a new trial of overcoming constraints regarding degradation stability, amorphous structure
nature, high potential of breakdown and band offsets process ability and reproducibility of …
nature, high potential of breakdown and band offsets process ability and reproducibility of …