User profiles for Abeer Madbouly

Abeer Madbouly

National Marrow Donor Program
Verified email at nmdp.org
Cited by 1356

[HTML][HTML] Six-locus high resolution HLA haplotype frequencies derived from mixed-resolution DNA typing for the entire US donor registry

L Gragert, A Madbouly, J Freeman, M Maiers - Human immunology, 2013 - Elsevier
We have calculated six-locus high resolution HLA A∼C∼B∼DRB3/4/5∼DRB1∼DQB1
haplotype frequencies using all Be The Match® Registry volunteer donors typed by DNA …

[HTML][HTML] Progress toward an efficient panel of SNPs for ancestry inference

…, AJ Pakstis, MR Furtado, R Fang, A Madbouly… - Forensic Science …, 2014 - Elsevier
Many panels of ancestry informative single nucleotide polymorphisms have been proposed
in recent years for various purposes including detecting stratification in biomedical studies …

Epitopes as characterized by antibody-verified eplet mismatches determine risk of kidney transplant loss

R Sapir-Pichhadze, X Zhang, A Ferradji, A Madbouly… - Kidney international, 2020 - Elsevier
To optimize strategies that mitigate the risk of graft loss associated with HLA incompatibility,
we evaluated whether sequence defined HLA targets (eplets) that result in donor-specific …

[HTML][HTML] HapLogic: a predictive human leukocyte antigen–matching algorithm to enhance rapid identification of the optimal unrelated hematopoietic stem cell sources …

…, B Beduhn, L Gragert, A Madbouly… - Biology of Blood and …, 2016 - Elsevier
The search for a suitable human leukocyte antigen (HLA)–matched unrelated adult stem cell
donor (URD) or umbilical cord blood unit (UCB) is a complex process. The National Marrow …

[HTML][HTML] A combined DPA1∼DPB1 amino acid epitope is the primary unit of selection on the HLA-DP heterodimer

JA Hollenbach, A Madbouly, L Gragert, C Vierra-Green… - Immunogenetics, 2012 - Springer
Here, we present results for DPA1 and DPB1 four-digit allele-level typing in a large (n =
5,944) sample of unrelated European American stem cell donors previously characterized for …

[HTML][HTML] Measuring ambiguity in HLA typing methods

V Paunić, L Gragert, A Madbouly, J Freeman, M Maiers - 2012 - journals.plos.org
In hematopoietic stem cell transplantation, donor selection is based primarily on matching
donor and patient HLA genes. These genes are highly polymorphic and their typing can result …

[HTML][HTML] MHC class I chain-related gene A (MICA) donor-recipient mismatches and MICA-129 polymorphism in unrelated donor hematopoietic cell transplantations …

…, T Wang, M Haagenson, N Majhail, A Madbouly… - Biology of Blood and …, 2017 - Elsevier
Single-center studies have previously reported associations of MHC Class I Chain-Related
Gene A (MICA) polymorphisms and donor-recipient MICA mismatching with graft-versus-host …

[HTML][HTML] Combined imputation of HLA genotype and self-identified race leads to better donor-recipient matching

S Israeli, L Gragert, A Madbouly, P Bashyal… - Human Immunology, 2023 - Elsevier
Allogeneic Hematopoietic Cell Transplantation (HCT) is a curative therapy for hematologic
disorders and often requires human leukocyte antigen (HLA)-matched donors. Donor …

High-resolution HLA A∼ B∼ DRB1 haplotype frequencies from the ezer mizion bone marrow donor registry in Israel

…, N Shriki, I Yaniv, B Zisser, M Maiers, A Madbouly… - Human immunology, 2016 - Elsevier
We have investigated HLA population alleles and haplotype frequencies for the ethnicities
that comprise the contemporary population of Israel, using a large data set from the Ezer …

Race, Ethnicity, Ancestry, and aspects that Impact HLA data and matching for transplant

A Madbouly, YT Bolon - Frontiers in Genetics, 2024 - frontiersin.org
Race, ethnicity, and ancestry are terms that are often misinterpreted and/or used interchangeably.
There is lack of consensus in the scientific literature on the definition of these terms …