To site-specifically incorporate an unnatural amino acid (UAA) into target proteins in Escherichia
coli, we use a suppressor plasmid that provides an engineered suppressor tRNA and …

Fluorescent reporters are useful in vitro and in vivo probes of protein structure, function, and
localization. Here we report that the fluorescent amino acid, 3-(6-acetylnaphthalen-2-ylamino…

The Orbiting Carbon Observatory-2 has been on orbit since 2014, and its global coverage
holds the potential to reveal new information about the carbon cycle through the use of top-…

Background Surgeons have increasingly performed breast-conserving surgery (BCS) utilizing
oncoplastic techniques in place of standard lumpectomy for early-stage breast cancer. We …

The ability to genetically incorporate unnatural amino acids (UAAs) at specific sites in the
proteome of living cells provides a powerful tool to both investigate and engineer protein …

Thiamine pyrophosphate 1 is an essential cofactor in all living systems 1 . Its biosynthesis
involves the separate syntheses of the pyrimidine 2 and thiazole 3 precursors, which are then …

Purpose Breast cancer surgical techniques are evolving. Few studies have analyzed
national trends for the multitude of surgical options that include partial mastectomy (PM), …

Purpose Enhanced recovery after surgery (ERAS) pathways are increasingly promoted in
post-mastectomy reconstruction, with several articles reporting their benefits and safety. This …

Background Several definitions of oncoplastic surgery have been reported in the literature. In
an effort to facilitate communication regarding oncoplastic surgery to patients, trainees, and …

4-Amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P) synthase catalyzes a
complex rearrangement of 5-aminoimidazole ribonucleotide (AIR) to form HMP-P, the …