Drugs and life-threatening ventricular arrhythmia risk: results from the DARE study cohort

AL Coughtrie, ER Behr, D Layton, V Marshall… - BMJ open, 2017 - bmjopen.bmj.com
Objectives To establish a unique sample of proarrhythmia cases, determine the
characteristics of cases and estimate the contribution of individual drugs to the incidence of …

Ecology and diversity in upper respiratory tract microbial population structures from a cross-sectional community swabbing study

AL Coughtrie, DE Morris… - Journal of Medical …, 2018 - microbiologyresearch.org
Purpose. Respiratory tract infections (RTIs) are responsible for over 2.8 million deaths per
year worldwide with pathobiont carriage a required precursor to infection. We sought to …

Microbial epidemiology and carriage studies for the evaluation of vaccines

AL Coughtrie, JM Jefferies… - Journal of Medical …, 2019 - microbiologyresearch.org
Respiratory tract infections are responsible for over 2.8 million deaths per year worldwide.
Colonization is the first step in the process of microbes occupying the respiratory tract, which …

Utilisation and tolerability of aliskiren in the primary care setting in England

AL Coughtrie, C Doe, D Layton… - The Journal of Clinical …, 2016 - Wiley Online Library
Aliskiren (Rasilez), a direct renin inhibitor, is indicated for the treatment of essential
hypertension. A postmarketing prescription‐event monitoring ( PEM ) study was conducted in …

Pattern of Onset and Risk Factors for Peripheral Oedema During Vildagliptin Use: Analysis from the Vildagliptin Prescription–Event Monitoring Study in England

D Layton, AL Coughtrie, N Qayum, SAW Shakir - Drug safety, 2016 - Springer
Introduction Clinical trials have identified peripheral oedema (PO) as an adverse event of
vildagliptin (an oral anti-diabetic drug [OAD]). A post-marketing study (PMS) was conducted to …

Epidemiological and ecological modelling reveal diversity in upper respiratory tract microbial population structures from a cross-sectional community swabbing study

AL Coughtrie, DE Morris, R Anderson, N Begum… - bioRxiv, 2017 - biorxiv.org
Respiratory tract infections (RTI) are responsible for over 4 million deaths per year
worldwide with pathobiont carriage a required precursor to infection. Through a cross-sectional …

[HTML][HTML] Microbial analysis of the upper respiratory tract to support the development of effective vaccine policy: a population-based pilot study

AL Coughtrie, RN Whittaker, N Begum, R Anderson… - The Lancet, 2012 - thelancet.com
Background Respiratory infections cause 7% of deaths globally. Microbial upper respiratory
tract (URT) carriage is a precursor to respiratory disease, meningitis, and septicaemia. …

[PDF][PDF] Epidemiology and ecology of microbial communities of the upper respiratory tract

A Coughtrie - 2015 - eprints.soton.ac.uk
… by Abigail Lois Coughtrie … I, Abigail Coughtrie, declare that this thesis and the work presented
in it are my own and has been generated by me as the result of my own original research. …

The characterization of Moraxella catarrhalis carried in the general population

DE Morris, KL Osman, DW Cleary… - Microbial …, 2022 - microbiologyresearch.org
Moraxella catarrhalis is a common cause of respiratory tract infection, particularly otitis media
in children, whilst it is also associated with the onset of exacerbation in chronic obstructive …

Risk management and outcomes of adverse events to pioglitazone in primary care in the UK: an observational study

C Fogg, R Kasliwal, SAW Shakir - Drug safety, 2009 - Springer
Background: Pioglitazone is an antidiabetic drug that belongs to the thiazolidinedione (TZD)
class of insulin-sensitizing agents. Adverse events to pioglitazone of potential severity are …