User profiles for Abigail Lind

Abigail Lind

Assistant Professor, Georgia Institute of Technology
Verified email at gatech.edu
Cited by 1836

Evolutionary constraint and innovation across hundreds of placental mammals

…, B Kirilenko, A Kowalczyk, C Lawless, AL Lind… - Science, 2023 - science.org
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

[HTML][HTML] Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species

AL Lind, JH Wisecaver, C Lameiras, P Wiemann… - PLoS …, 2017 - journals.plos.org
Filamentous fungi produce a diverse array of secondary metabolites (SMs) critical for defense,
virulence, and communication. The metabolic pathways that produce SMs are found in …

The birth, evolution and death of metabolic gene clusters in fungi

A Rokas, JH Wisecaver, AL Lind - Nature Reviews Microbiology, 2018 - nature.com
Fungi contain a remarkable diversity of both primary and secondary metabolic pathways
involved in ecologically specialized or accessory functions. Genes in these pathways are …

Mammalian evolution of human cis-regulatory elements and transcription factor binding sites

…, T Lehmann, DL Levesque, HA Lewin, X Li, A Lind… - Science, 2023 - science.org
Understanding the regulatory landscape of the human genome is a long-standing objective
of modern biology. Using the reference-free alignment across 241 mammalian genomes …

[HTML][HTML] Accurate and sensitive detection of microbial eukaryotes from whole metagenome shotgun sequencing

AL Lind, KS Pollard - Microbiome, 2021 - Springer
Background Microbial eukaryotes are found alongside bacteria and archaea in natural microbial
systems, including host-associated microbiomes. While microbial eukaryotes are critical …

A Robust Phylogenomic Time Tree for Biotechnologically and Medically Important Fungi in the Genera Aspergillus and Penicillium

JL Steenwyk, XX Shen, AL Lind, GH Goldman, A Rokas - MBio, 2019 - Am Soc Microbiol
The filamentous fungal family Aspergillaceae contains >1,000 known species, mostly in the
genera Aspergillus and Penicillium. Several species are used in the food, biotechnology, …

Nanoscale architecture of the Schizosaccharomyces pombe contractile ring

NA McDonald, AL Lind, SE Smith, R Li, KL Gould - Elife, 2017 - elifesciences.org
10.7554/eLife.28865.001 The contractile ring is a complex molecular apparatus which
physically divides many eukaryotic cells. Despite knowledge of its protein composition, the …

[HTML][HTML] Examining the Evolution of the Regulatory Circuit Controlling Secondary Metabolism and Development in the Fungal Genus Aspergillus

AL Lind, JH Wisecaver, TD Smith, X Feng… - PLoS …, 2015 - journals.plos.org
Filamentous fungi produce diverse secondary metabolites (SMs) essential to their ecology
and adaptation. Although each SM is typically produced by only a handful of species, global …

[HTML][HTML] Genome of the Komodo dragon reveals adaptations in the cardiovascular and chemosensory systems of monitor lizards

AL Lind, YYY Lai, Y Mostovoy, AK Holloway… - Nature ecology & …, 2019 - nature.com
Monitor lizards are unique among ectothermic reptiles in that they have high aerobic capacity
and distinctive cardiovascular physiology resembling that of endothermic mammals. Here, …

Regulation of Secondary Metabolism by the Velvet Complex Is Temperature-Responsive in Aspergillus

AL Lind, TD Smith, T Saterlee… - G3: Genes, Genomes …, 2016 - academic.oup.com
Sensing and responding to environmental cues is critical to the lifestyle of filamentous fungi.
How environmental variation influences fungi to produce a wide diversity of ecologically …