[HTML][HTML] Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

…, S Trompet, B Tyl, AG Uitterlinden, A Veluchamy… - Nature …, 2020 - nature.com
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion
of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide …

[HTML][HTML] Risk factors for neuropathic pain in diabetes mellitus

HL Hébert, A Veluchamy, N Torrance, BH Smith - Pain, 2017 - journals.lww.com
According to the International Diabetes Federation, diabetes mellitus (DM) is estimated to
affect around 415 million adults worldwide, roughly 8.8% of the adult population, with the …

Cohort profile: genetics of diabetes audit and research in Tayside Scotland (GoDARTS)

…, B Shepherd, K Milburn, A Veluchamy… - International journal …, 2018 - academic.oup.com
The prevalence of diabetes worldwide has been steadily increasing over the past 20 years.
In 1997 it was estimated to be 124 million, 1 in 2015 it was estimated to be 415 million …

[HTML][HTML] Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function

…, SK Madanagopal, A Taylor, S Bell, A Veluchamy… - Diabetologia, 2022 - Springer
Aims/hypothesis South Asians in general, and Asian Indians in particular, have higher risk of
type 2 diabetes compared with white Europeans, and a younger age of onset. The reasons …

[HTML][HTML] Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland

N Torrance, A Veluchamy, Y Zhou, EH Fletcher… - British journal of …, 2020 - Elsevier
Background Gabapentinoid drugs (gabapentin and pregabalin) are effective in neuropathic
pain, which has a prevalence of ∼7%. Concerns about increased prescribing have …

Neuropathic pain in the community: prevalence, impact, and risk factors

BH Smith, HL Hébert, A Veluchamy - Pain, 2020 - journals.lww.com
Neuropathic pain arises as a direct consequence of a lesion or disease affecting the
somatosensory system. 87 It can be peripheral in origin, as a result of nerve injury or disease (eg, …

Joint European Academy of Neurology–European Pain Federation–Neuropathic Pain Special Interest Group of the International Association for the Study of Pain …

…, T Tölle, J Valls‐Solé, A Veluchamy - European Journal of …, 2023 - Wiley Online Library
Background and Purpose In these guidelines, we aimed to develop evidence‐based
recommendations for the use of screening questionnaires and diagnostic tests in patients with …

Systematic review and meta-analysis of genetic risk factors for neuropathic pain

A Veluchamy, HL Hebert, W Meng, CNA Palmer… - Pain, 2018 - journals.lww.com
Neuropathic pain (NP) is an increasingly common chronic pain state and a major health
burden, affecting approximately 7% to 10% of the general population. Emerging evidence …

[HTML][HTML] A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

…, SS Verma, CG Chute, A Veluchamy… - The …, 2016 - nature.com
The most common side effect of angiotensin-converting enzyme inhibitor (ACEi) drugs is
cough. We conducted a genome-wide association study (GWAS) of ACEi-induced cough …

A common missense variant of LILRB5 is associated with statin intolerance and myalgia

MK Siddiqui, C Maroteau, A Veluchamy… - European heart …, 2017 - academic.oup.com
Aims A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366:
T > C: Asp247Gly) has been reported to be associated with lower creatine …