Abstract Development of the forebrain critically depends on the Sonic Hedgehog (Shh)
signaling pathway, as illustrated in humans by the frequent perturbation of this pathway in …

Primary cilia are essential for CNS development. In the mouse, they play a critical role in
patterning the spinal cord and telencephalon via the regulation of Hedgehog/Gli signaling. …

During the development of the central nervous system, the immature neurons suffer different
migration processes. It is well known that Nkx2.1-positive ventricular layer give rise to …

Dysfunction of the LIS1 gene causes lissencephaly, a drastic neurological disorder
characterized by a deep disruption of the cortical structure. We aim to uncover alterations of the …

Cilia-related proteins are believed to be involved in a broad range of cellular processes.
Retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) is a ciliary protein …

The fasciculus retroflexus is an important fascicle that mediates reward-related behaviors
and is associated with different psychiatric diseases. It is the main habenular efference and …

Wnt1 is one of the morphogenes that controls the specification and differentiation of neuronal
populations in the developing central nervous system. The habenula is a diencephalic …

A crucial event during the development of the central nervous system (CNS) is the early
subdivision of the neural tube along its anterior-to-posterior axis to form neuromeres, …

Background The fasciculus retroflexus is the prominent efferent pathway from the habenular
complex. Medial habenular axons form a core packet whereas lateral habenular axons …

The vertebrate brain is a remarkably complex anatomical structure which contains diverse
subdivisions and neuronal subtypes with specific synaptic connections that contribute to the …