User profiles for Adam D. Kashlan
Adam KashlanFM Kirby Neurobiology Center, Boston Children's Hospital Verified email at gatech.edu Cited by 114 |
DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels
Videos of animal behavior are used to quantify researcher-defined behaviors of interest to
study neural function, gene mutations, and pharmacological therapies. Behaviors of interest …
study neural function, gene mutations, and pharmacological therapies. Behaviors of interest …
Development and validation of painface, a software platform that simplifies and standardizes mouse grimace analyses
…, LV Lima, SG Sotocinal, JS Austin, AD Kashlan… - The Journal of …, 2023 - Elsevier
Facial grimaces are now commonly used to quantify spontaneous pain in mice and other
mammalian species, but scoring remains subjective and relies on humans with very different …
mammalian species, but scoring remains subjective and relies on humans with very different …
Development and validation of PainFace, a software platform that simplifies and standardizes mouse grimace analyses
…, LV Lima, SG Sotocinal, JS Austin, AD Kashlan… - bioRxiv, 2022 - biorxiv.org
Facial grimaces are now commonly used to quantify spontaneous pain in mice and other
mammalian species, but scoring remains subjective and relies on humans with very different …
mammalian species, but scoring remains subjective and relies on humans with very different …
Development of PainFace software to simplify, standardize, and scale up mouse grimace analyses
…, LV Lima, SG Sotocinal, JS Austin, AD Kashlan… - Pain, 2022 - journals.lww.com
Facial grimacing is used to quantify spontaneous pain in mice and other mammals, but
scoring relies on humans with different levels of proficiency. Here, we developed a cloud-based …
scoring relies on humans with different levels of proficiency. Here, we developed a cloud-based …
Lhs1 dependent ERAD is determined by transmembrane domain context
…, S Shi, TR Kleyman, OB Kashlan… - Biochemical …, 2023 - portlandpress.com
Transmembrane proteins have unique requirements to fold and integrate into the endoplasmic
reticulum (ER) membrane. Most notably, transmembrane proteins must fold in three …
reticulum (ER) membrane. Most notably, transmembrane proteins must fold in three …
Parabrachial Hyperexcitability In A Mouse Model Of Neuropathic Pain
MT Suarez, N Cramer, B Neugebauer, K Flores-Felix… - The Journal of …, 2023 - Elsevier
The parabrachial nucleus (PBN) is an important sensory processing and relay station for
pain neurotransmission. Data from in vivo and histological studies have shown that PBN …
pain neurotransmission. Data from in vivo and histological studies have shown that PBN …
Epithelial Na+ channel regulation by cytoplasmic and extracellular factors
OB Kashlan, TR Kleyman - Experimental cell research, 2012 - Elsevier
Electrogenic Na + transport across high resistance epithelial is mediated by the epithelial
Na + channel (ENaC). Our understanding of the mechanisms of ENaC regulation has …
Na + channel (ENaC). Our understanding of the mechanisms of ENaC regulation has …
Dynamic Role Of Locus Coeruleus Mu Opioid Receptor Function In Nociceptive Processing
Dissecting discrete neural circuitry is critical to understanding how pain processing may be
altered in the transition from acute to chronic, maladaptive pain. The locus coeruleus (LC) …
altered in the transition from acute to chronic, maladaptive pain. The locus coeruleus (LC) …
Multiple motifs regulate apical sorting of p75 via a mechanism that involves dimerization and higher-order oligomerization
…, SA Costa, Y Rbaibi, F Lanni, OB Kashlan… - Molecular biology of …, 2013 - Am Soc Cell Biol
The sorting signals that direct proteins to the apical surface of polarized epithelial cells are
complex and can include posttranslational modifications, such as N- and O-linked …
complex and can include posttranslational modifications, such as N- and O-linked …
Reversible electrocochleographic abnormalities in superior canal dehiscence
HA Arts, ME Adams, SA Telian, H El-Kashlan… - Otology & …, 2009 - journals.lww.com
Objective: Electrocochleography (ECoG) is often used in the evaluation of episodic vertigo,
and abnormal findings are commonly thought to be due to endolymphatic hydrops. We have …
and abnormal findings are commonly thought to be due to endolymphatic hydrops. We have …