User profiles for Adam Godzik

Adam Godzik

Professor, University of California Riverside School of Medicine
Verified email at medsch.ucr.edu
Cited by 54282

Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences

W Li, A Godzik - Bioinformatics, 2006 - academic.oup.com
Motivation: In 2001 and 2002, we published two papers (Bioinformatics, 17, 282–283,
Bioinformatics, 18, 77–82) describing an ultrafast protein sequence clustering program called cd-…

[HTML][HTML] Detection of a SARS-CoV-2 variant of concern in South Africa

…, O Laguda-Akingba, A Alisoltani-Dehkordi, A Godzik… - Nature, 2021 - nature.com
Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating
conditions for substantial evolutionary changes to the virus 1 , 2 . Here we describe a newly …

Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa

…, O Laguda-Akingba, A Alisoltani-Dehkordi, A Godzik… - medrxiv, 2020 - medrxiv.org
Continued uncontrolled transmission of the severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for significant …

[HTML][HTML] Protein tyrosine phosphatases in the human genome

…, I Friedberg, I Friedberg, A Osterman, A Godzik… - Cell, 2004 - cell.com
Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by
90 genes in the human genome. Here, we present the set of 107 genes in the human …

S-nitrosylation of Drp1 mediates β-amyloid-related mitochondrial fission and neuronal injury

DH Cho, T Nakamura, J Fang, P Cieplak, A Godzik… - Science, 2009 - science.org
Mitochondria continuously undergo two opposing processes, fission and fusion. The
disruption of this dynamic equilibrium may herald cell injury or death and may contribute to …

Clustering of highly homologous sequences to reduce the size of large protein databases

W Li, L Jaroszewski, A Godzik - Bioinformatics, 2001 - academic.oup.com
We present a fast and flexible program for clustering large protein databases at different
sequence identity levels. It takes less than 2 h for the all-against-all sequence comparison and …

[PDF][PDF] The NLR gene family: a standard nomenclature

…, JM Boss, BK Davis, RA Flavell, SE Girardin, A Godzik… - Immunity, 2008 - cell.com
Immune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, and cryopyrin
(also known as NALP3) are members of a family characterized by the presence of a NACHT …

[HTML][HTML] The Sorcerer II Global Ocean Sampling Expedition: Expanding the Universe of Protein Families

…, V Bafna, R Friedman, SE Brenner, A Godzik… - PLoS …, 2007 - journals.plos.org
Metagenomics projects based on shotgun sequencing of populations of micro-organisms
yield insight into protein families. We used sequence similarity clustering to explore proteins …

[HTML][HTML] A primer on metagenomics

JC Wooley, A Godzik, I Friedberg - PLoS computational biology, 2010 - journals.plos.org
Metagenomics is a discipline that enables the genomic study of uncultured microorganisms.
Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes …

[PDF][PDF] Flexible structure alignment by chaining aligned fragment pairs allowing twists

Y Ye, A Godzik - Bioinformatics, 2003 - user.ceng.metu.edu.tr
Motivation: Protein structures are flexible and undergo structural rearrangements as part of
their function, and yet most existing protein structure comparison methods treat them as rigid …