[HTML][HTML] Widespread natural variation of DNA methylation within angiosperms

CE Niederhuth, AJ Bewick, L Ji, MS Alabady, KD Kim… - Genome biology, 2016 - Springer
Background DNA methylation is an important feature of plant epigenomes, involved in the
formation of heterochromatin and affecting gene expression. Extensive variation of DNA …

Gene body DNA methylation in plants

AJ Bewick, RJ Schmitz - Current opinion in plant biology, 2017 - Elsevier
… Author links open overlay panel Adam J Bewick , Robert J Schmitz … In the model proposed
by Bewick et al. [17 •• ], (a) rare events where IBM1 fails to remove H3K9me2 leads to (b) …

Evolution of DNA methylation across insects

AJ Bewick, KJ Vogel, AJ Moore… - Molecular biology and …, 2017 - academic.oup.com
DNA methylation contributes to gene and transcriptional regulation in eukaryotes, and
therefore has been hypothesized to facilitate the evolution of plastic traits such as sociality in …

Widespread adenine N6-methylation of active genes in fungi

…, RO Dannebaum, RC Kuo, KB Louie, AJ Bewick… - Nature …, 2017 - nature.com
N6-methyldeoxyadenine (6mA) is a noncanonical DNA base modification present at low levels
in plant and animal genomes 1 , 2 , 3 , 4 , but its prevalence and association with genome …

On the origin and evolutionary consequences of gene body DNA methylation

AJ Bewick, L Ji, CE Niederhuth… - Proceedings of the …, 2016 - National Acad Sciences
In plants, CG DNA methylation is prevalent in the transcribed regions of many constitutively
expressed genes (gene body methylation; gbM), but the origin and function of gbM remain …

Subgenome dominance in an interspecific hybrid, synthetic allopolyploid, and a 140-year-old naturally established neo-allopolyploid monkeyflower

…, AM Cooley, M Vallejo-Marin, Y Yuan, AJ Bewick… - The Plant …, 2017 - academic.oup.com
Recent studies have shown that one of the parental subgenomes in ancient polyploids is
generally more dominant, having retained more genes and being more highly expressed, a …

[HTML][HTML] The evolution of CHROMOMETHYLASES and gene body DNA methylation in plants

AJ Bewick, CE Niederhuth, L Ji, NA Rohr, PT Griffin… - Genome biology, 2017 - Springer
Background The evolution of gene body methylation (gbM), its origins, and its functional
consequences are poorly understood. By pairing the largest collection of transcriptomes (>1000…

Diversity of cytosine methylation across the fungal tree of life

AJ Bewick, BT Hofmeister, RA Powers… - Nature ecology & …, 2019 - nature.com
The generation of thousands of fungal genomes is leading to a better understanding of genes
and genomic organization within the kingdom. However, the epigenome, which includes …

Firefly genomes illuminate parallel origins of bioluminescence in beetles

…, CH Chang, M Bessho-Uehara, GJ Martin, AJ Bewick… - elife, 2018 - elifesciences.org
10.7554/eLife.36495.001 Fireflies and their luminous courtships have inspired centuries of
scientific study. Today firefly luciferase is widely used in biotechnology, but the evolutionary …

EVOLUTION OF THE CLOSELY RELATED, SEX‐RELATED GENES DM‐W AND DMRT1 IN AFRICAN CLAWED FROGS (XENOPUS)

AJ Bewick, DW Anderson, BJ Evans - Evolution, 2011 - academic.oup.com
DM‐W is a dominant, female‐specific, regulator of sex determination in the African clawed
frog Xenopus laevis. This gene is derived from partial duplication of DMRT1, a male‐related …