We have developed a reactor-scale model of Escherichia coli metabolism and growth in a
1000L process for the production of a recombinant therapeutic protein. The model consists of …

Selective estrogen receptor (ER) modulators are highly successful breast cancer therapies,
but they are not effective in patients with ER negative and selective estrogen receptor …

A bio-based economy has the potential to provide sustainable substitutes for petroleum-based
products and new chemical building blocks for advanced materials. We previously …

We observed that removing pantothenate (vitamin B 5 ), a precursor to co-enzyme A, from the
growth medium of Saccharomyces cerevisiae engineered to produce β-farnesene reduced …

It has been proposed that during growth under anaerobic or oxygen-limited conditions,
Shewanella oneidensis MR-1 uses the serine-isocitrate lyase pathway common to many …

Aerobic growth of Shewanella oneidensis MR‐1 in minimal lactate medium was studied in
batch cultivation. Acetate production was observed in the middle of the exponential growth …

The metabolic and morphological characteristics of two human epithelial breast cell
populations‐MCF7 cells, a cancerous cell line, and 48R human mammary epithelial cells (48R …

Engineering microbes to synthesize molecules of societal value has historically been a time
consuming and artisanal process, with the synthesis of each new non-native molecule …

Metabolic flux analysis (MFA) is widely used to quantify metabolic pathway activity. Typical
applications involve isotopically labeled substrates, which require both metabolic and …

Protein self-assembly is a particularly attractive option for bottom-up creation of tunable smart
materials and functional devices.[1, 2] As display technologies have unleashed a plethora …