Extent of surgery for papillary thyroid cancer is not associated with survival: an analysis of 61,775 patients

MA Adam, J Pura, L Gu, MA Dinan, DS Tyler… - Annals of …, 2014 - journals.lww.com
Objective: To examine the association between the extent of surgery and overall survival in
a large contemporary cohort of patients with papillary thyroid cancer (PTC). Background: …

Presence and number of lymph node metastases are associated with compromised survival for patients younger than age 45 years with papillary thyroid cancer

MA Adam, J Pura, P Goffredo, MA Dinan… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Cervical lymph node metastases are recognized as a prognostic indicator only in
patients age 45 years or older with papillary thyroid cancer (PTC); patients younger than age …

Minimally invasive versus open pancreaticoduodenectomy for cancer: practice patterns and short-term outcomes among 7061 patients

MA Adam, K Choudhury, MA Dinan, SD Reed… - Annals of …, 2015 - journals.lww.com
Objectives: To describe national practice patterns regarding utilization of minimally invasive
pancreaticoduodenectomy (MIPD) and compare short-term outcomes with those following …

An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells

V Lulla, AM Dinan, M Hosmillo, Y Chaudhry… - Nature …, 2019 - nature.com
Enteroviruses comprise a large group of mammalian pathogens that includes poliovirus.
Pathology in humans ranges from sub-clinical to acute flaccid paralysis, myocarditis and …

Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria

…, AM Dinan, S Gopalakrishna, M Cipullo… - Nucleic acids …, 2023 - academic.oup.com
The synthesis of mitochondrial OXPHOS complexes is central to cellular metabolism, yet many
molecular details of mitochondrial translation remain elusive. It has been commonly held …

[HTML][HTML] Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies …

AA Miranda-CasoLuengo, PM Staunton, AM Dinan… - BMC genomics, 2016 - Springer
Background Mycobacterium abscessus subsp. abscessus (MAB) is a highly drug resistant
mycobacterium and the most common respiratory pathogen among the rapidly growing non-…

[PDF][PDF] Hybrid gene origination creates human-virus chimeric proteins during infection

…, M Chang, Y Fstkchyan, S Clohisey, AM Dinan… - Cell, 2020 - cell.com
RNA viruses are a major human health threat. The life cycles of many highly pathogenic RNA
viruses like influenza A virus (IAV) and Lassa virus depends on host mRNA, because viral …

A case for a negative-strand coding sequence in a group of positive-sense RNA viruses

AM Dinan, NI Lukhovitskaya, I Olendraite… - Virus …, 2020 - academic.oup.com
Positive-sense single-stranded RNA viruses form the largest and most diverse group of
eukaryote-infecting viruses. Their genomes comprise one or more segments of coding-sense …

Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression

GM Cook, K Brown, P Shang, Y Li, L Soday, AM Dinan… - Elife, 2022 - elifesciences.org
The arterivirus porcine reproductive and respiratory syndrome virus (PRRSV) causes
significant economic losses to the swine industry worldwide. Here we apply ribosome profiling (…

C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis

…, AM Dinan, FA Rosenberger, M Cipullo… - Nucleic acids …, 2019 - academic.oup.com
In all biological systems, RNAs are associated with RNA-binding proteins (RBPs), forming
complexes that control gene regulatory mechanisms, from RNA synthesis to decay. In …