User profiles for Adam Mechler

Adam Mechler

La Trobe University
Verified email at latrobe.edu.au
Cited by 5253

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

H Kalra, CG Adda, M Liem, CS Ang, A Mechler… - …, 2013 - Wiley Online Library
Exosomes are nanovesicles released by a variety of cells and are detected in body fluids
including blood. Recent studies have highlighted the critical application of exosomes as …

[HTML][HTML] Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes

…, M Liem, P Fonseka, I Atukorala, C Ozcitti, A Mechler… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) include the exosomes (30-100 nm) that are produced through
the endocytic pathway via the multivesicular bodies and the ectosomes (100-1000 nm) that …

Semiconductive polymer blends: Correlating structure with transport properties at the nanoscale

C Ionescu‐Zanetti, A Mechler, SA Carter… - Advanced …, 2004 - Wiley Online Library
Multimodal atomic force microscopy (AFM) was used to map charge transfer properties in
correlation to the molecular superstructure of poly(ethyldioxythiophene)–poly(styrenesulfonic …

[HTML][HTML] Calcium-dependent open/closed conformations and interfacial energy maps of reconstituted hemichannels

J Thimm, A Mechler, H Lin, S Rhee, R Lal - Journal of Biological Chemistry, 2005 - ASBMB
Using an atomic force microscope, we have studied three-dimensional molecular topography
and calcium-sensitive conformational changes of individual hemichannels. Full-length (non…

[HTML][HTML] Specific and selective peptide-membrane interactions revealed using quartz crystal microbalance

A Mechler, S Praporski, K Atmuri, M Boland… - Biophysical …, 2007 - cell.com
The skin secretions of Australian tree frogs are rich in peptides with potential antimicrobial
activity. They interrupt bacterial cell membranes, although precisely how and whether all …

Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens

…, S Piantavigna, A Hansen, A Mechler… - Journal of medicinal …, 2010 - ACS Publications
Small proline-rich antimicrobial peptides (AMP) have attracted considerable interest, as they
target specific intracellular bacterial components and do not act by lytic mechanisms. Here, …

Theoretical and experimental studies of the antioxidant and antinitrosant activity of syringic acid

…, DT Quang, M Flavel, NT Hoa, A Mechler - The Journal of …, 2020 - ACS Publications
Syringic acid (SA) is a natural phenolic acid found in vegetables, fruits, and other plant-based
foods. A range of biological activities were proposed for this compound including …

Evaporative self-assembly assisted synthesis of polymeric nanoparticles by surface acoustic wave atomization

JR Friend, LY Yeo, DR Arifin, A Mechler - Nanotechnology, 2008 - iopscience.iop.org
We demonstrate a straightforward and rapid atomization process driven by surface acoustic
waves that is capable of continuously producing spherical monodispersed submicron poly-ε-…

[HTML][HTML] Membrane core-specific antimicrobial action of cathelicidin LL-37 peptide switches between pore and nanofibre formation

…, CG Adda, BJ Smith, MA Perugini, A Mechler - Scientific reports, 2016 - nature.com
Membrane-disrupting antimicrobial peptides provide broad-spectrum defence against
localized bacterial invasion in a range of hosts including humans. The most generally held …

[HTML][HTML] Density functional theory study of the role of benzylic hydrogen atoms in the antioxidant properties of lignans

…, PC Nam, MV Bay, NM Thong, ND Cuong, A Mechler - Scientific reports, 2018 - nature.com
Antioxidants are a diverse group of chemicals with proven health benefits and thus potential
preventive medicine and therapeutic applications. While most of these compounds are …