Proper preimplantation development is essential to assemble a blastocyst capable of
implantation. Live imaging has uncovered major events driving early development in mouse …

During preimplantation development, contractile forces generated at the apical cortex segregate
cells into inner and outer positions of the embryo, establishing the inner cell mass (ICM) …

During mammalian development, the first asymmetric cell divisions segregate cells into inner
and outer positions of the embryo to establish the pluripotent and trophectoderm lineages. …

Many amniote vertebrate species including humans can form identical twins from a single
embryo, but this only occurs rarely. It has been suggested that the primitive-streak-forming …

In warm-blooded vertebrate embryos (mammals and birds), the axial tissues of the body form
from a growth zone at the tail end, Hensen’s node, which generates neural, mesodermal, …

Somites are transient structures derived from the pre‐somitic mesoderm (PSM), involving
mesenchyme‐to‐epithelial transition (MET) where the cells change their shape and polarize. …

We present a detailed analysis of gene expression in the 2-day (HH12) embryonic chick heart.
RNA-seq of 13 micro-dissected regions reveals regionalised expression of 15,570 genes. …

In this issue of Developmental Cell, Arekatla et al. use optogenetic technologies to dissect
the roles of ERK and AKT dynamics in pluripotency. They show how mouse embryonic stem …

Increasing age is the main risk factor for chronic lung diseases (CLD) including idiopathic
pulmonary fibrosis (IPF). Halting or reversing progression of IPF remains an unmet clinical …

In warm-blooded vertebrate embryos (mammals and birds), the body forms from a growth
zone at the tail end. Hensen’s node, a region which induces and patterns the neural axis is …