A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens… - Nature …, 2018 - nature.com
Primary cilia organize Hedgehog signaling and shape embryonic development, and their
dysregulation is the unifying cause of ciliopathies. We conducted a functional genomic screen …

[HTML][HTML] Medical student remote eConsult participation during the COVID-19 pandemic

AR Kopp, S Rikin, T Cassese, MA Berger, AC Raff… - BMC medical …, 2021 - Springer
Background Undergraduate medical education was severely impacted by the COVID-19
pandemic. As traditional clinical rotations were suspended, medical students quickly began …

A comprehensive portrait of cilia and ciliopathies from a CRISPR-based screen for hedgehog signaling

DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens… - bioRxiv, 2017 - biorxiv.org
The primary cilium organizes Hedgehog signaling, shapes embryonic development and is
the unifying cause of the ciliopathies. We conducted a functional genomic screen for …

getABI: German epidemiological trial on ankle brachial index for elderly patients in family practice to dedect peripheral arterial disease, significant marker for high …

…, J Wrobel, I Ackermann, R Adams… - Vasa-Journal of …, 2002 - vivantes.elsevierpure.com
Background: Peripheral arterial occlusive disease (PAD) is a common, but widely underestimated
disease associated with a high morbidity and mortality risk. PAD can be regarded as …

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

AP Kusumbe, SK Ramasamy, RH Adams - Nature, 2014 - nature.com
The mammalian skeletal system harbours a hierarchical system of mesenchymal stem cells,
osteoprogenitors and osteoblasts sustaining lifelong bone formation. Osteogenesis is …

A reassessment of the economic effects of ozone on US agriculture

RM Adams, JD Glyer, SL Johnson, BA McCarl - Japca, 1989 - Taylor & Francis
… methodology is the same as that described in Adams, Hamilton, and McCarl.The primary
differences between the structure of the economic analysis reported in Adams, Hamilton, and …

Probabilistic assessment of sea level during the last interglacial stage

RE Kopp, FJ Simons, JX Mitrovica, AC Maloof… - Nature, 2009 - nature.com
With polar temperatures ∼3–5 C warmer than today, the last interglacial stage (∼125 kyr
ago) serves as a partial analogue for 1–2 C global warming scenarios. Geological records …

Oxidative stress response of rainbow trout (Oncorhynchus mykiss) to multiple stressors

R Kopp, M Palíková, I Papežíková, J Mareš… - Acta Veterinaria …, 2018 - actavet.vfu.cz
Fish can be exposed to multiple stressors at the same time, including natural toxins,
environmental pollutants or feed contamination. In this study, we report on the effects of controlled …

Towards a pan-European consensus on the treatment of patients with colorectal liver metastases

E Van Cutsem, B Nordlinger, R Adam… - European journal of …, 2006 - Elsevier
… of the number of patients who undergo R 0 resection versus R 1 or R 2 resection. A prospective
… However, in a separate study, Adam et al. demonstrated that response to preoperative …

The benefits of pollution control: the case of ozone and US Agriculture

RM Adams, SA Hamilton… - American Journal of …, 1986 - Wiley Online Library
… A recent study by Kopp, Vaughn, and Hazilla employs a more rigorous and defensible …
In terms of an ozone assumption, the Kopp, Vaughn, and Hazilla analysis is somewhat …