Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …
Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial
…, A Shabsigh, DA Barocas, ML Quek, A Dash, AS Kibel… - The Lancet, 2018 - thelancet.com
Background Radical cystectomy is the surgical standard for invasive bladder cancer. Robot-assisted
cystectomy has been proposed to provide similar oncological outcomes with lower …
cystectomy has been proposed to provide similar oncological outcomes with lower …
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
…, D Leongamornlert, S Lindstrom, S Jugurnauth-Little… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify additional …
prostate cancer risk predominantly in populations of European ancestry. To identify additional …
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
…, C Maier, T Schnoeller, M Luedeke, AS Kibel… - Nature …, 2021 - nature.com
Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer
Prostate cancers are considered to be immunologically ‘cold’ tumors given the very few
patients who respond to checkpoint inhibitor (CPI) therapy. Recently, enrichment of interferon-…
patients who respond to checkpoint inhibitor (CPI) therapy. Recently, enrichment of interferon-…
Prediction of erectile function following treatment for prostate cancer
Context Sexual function is the health-related quality of life (HRQOL) domain most commonly
impaired after prostate cancer treatment; however, validated tools to enable personalized …
impaired after prostate cancer treatment; however, validated tools to enable personalized …
11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse
…, KC Fischer, JM Michalski, AS Kibel… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Patients with rising prostate-specific antigen (PSA) levels after definitive local therapy of
prostate carcinoma present a diagnostic dilemma. A local recurrence would be amenable to …
prostate carcinoma present a diagnostic dilemma. A local recurrence would be amenable to …
[HTML][HTML] Global patterns of prostate cancer incidence, aggressiveness, and mortality in men of african descent
Prostate cancer (CaP) is the leading cancer among men of African descent in the USA,
Caribbean, and Sub-Saharan Africa (SSA). The estimated number of CaP deaths in SSA during …
Caribbean, and Sub-Saharan Africa (SSA). The estimated number of CaP deaths in SSA during …
Advanced prostate cancer: AUA/ASTRO/SUO guideline part I
…, T Crispino, R Dreicer, DF Jarrard, AS Kibel… - The Journal of …, 2021 - auajournals.org
Purpose: The summary presented herein represents Part I of the two-part series dedicated
to Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline discussing prognostic and …
to Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline discussing prognostic and …