Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

…, MC Southey, RJ MacInnis, LM FitzGerald, AS Kibel… - Nature …, 2018 - nature.com
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

…, S Lindstrom, P Kraft, DJ Hunter, S Gapstur… - Nature …, 2013 - nature.com
Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial

…, A Shabsigh, DA Barocas, ML Quek, A Dash, AS Kibel… - The Lancet, 2018 - thelancet.com
Background Radical cystectomy is the surgical standard for invasive bladder cancer. Robot-assisted
cystectomy has been proposed to provide similar oncological outcomes with lower …

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

…, D Leongamornlert, S Lindstrom, S Jugurnauth-Little… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify additional …

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

…, C Maier, T Schnoeller, M Luedeke, AS Kibel… - Nature …, 2021 - nature.com
Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer

…, P Galbo, S Panja, A Mitrofanova, S Wilkinson… - Nature cancer, 2021 - nature.com
Prostate cancers are considered to be immunologically ‘cold’ tumors given the very few
patients who respond to checkpoint inhibitor (CPI) therapy. Recently, enrichment of interferon-…

Prediction of erectile function following treatment for prostate cancer

…, N Sadetsky, CS Saigal, MS Litwin, E Klein, AS Kibel… - Jama, 2011 - jamanetwork.com
Context Sexual function is the health-related quality of life (HRQOL) domain most commonly
impaired after prostate cancer treatment; however, validated tools to enable personalized …

11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse

…, KC Fischer, JM Michalski, AS Kibel… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Patients with rising prostate-specific antigen (PSA) levels after definitive local therapy of
prostate carcinoma present a diagnostic dilemma. A local recurrence would be amenable to …

[HTML][HTML] Global patterns of prostate cancer incidence, aggressiveness, and mortality in men of african descent

…, SA Ingles, W Isaacs, M Jalloh, EM John, AS Kibel… - Prostate cancer, 2013 - hindawi.com
Prostate cancer (CaP) is the leading cancer among men of African descent in the USA,
Caribbean, and Sub-Saharan Africa (SSA). The estimated number of CaP deaths in SSA during …

Advanced prostate cancer: AUA/ASTRO/SUO guideline part I

…, T Crispino, R Dreicer, DF Jarrard, AS Kibel… - The Journal of …, 2021 - auajournals.org
Purpose: The summary presented herein represents Part I of the two-part series dedicated
to Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline discussing prognostic and …