Electrochemical detection of a single cytomegalovirus at an ultramicroelectrode and its antibody anchoring
We report observations of stochastic collisions of murine cytomegalovirus (MCMV) on
ultramicroelectrodes (UMEs), extending the observation of discrete collision events on UMEs to …
ultramicroelectrodes (UMEs), extending the observation of discrete collision events on UMEs to …
Enzymatically enhanced collisions on ultramicroelectrodes for specific and rapid detection of individual viruses
JE Dick, AT Hilterbrand, LM Strawsine… - Proceedings of the …, 2016 - National Acad Sciences
We report the specific collision of a single murine cytomegalovirus (MCMV) on a platinum
ultramicroelectrode (UME, radius of 1 μm). Antibody directed against the viral surface protein …
ultramicroelectrode (UME, radius of 1 μm). Antibody directed against the viral surface protein …
Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection
…, P Pisitkun, JP Jorgensen, AT Hilterbrand… - The Journal of …, 2015 - journals.aai.org
Herpesviruses are DNA viruses harboring the capacity to establish lifelong latent-recurrent
infections. There is limited knowledge about viruses targeting the innate DNA-sensing …
infections. There is limited knowledge about viruses targeting the innate DNA-sensing …
[HTML][HTML] Go go gadget glycoprotein!: HSV-1 draws on its sizeable glycoprotein tool kit to customize its diverse entry routes
AT Hilterbrand, EE Heldwein - PLoS Pathogens, 2019 - journals.plos.org
All viruses must enter cells to replicate [1]. Entry is thus the first hurdle a virus must overcome
for a successful infection. Given the astonishing diversity of viruses that infect mammals …
for a successful infection. Given the astonishing diversity of viruses that infect mammals …
Contributions of the four essential entry glycoproteins to HSV-1 tropism and the selection of entry routes
AT Hilterbrand, RE Daly, EE Heldwein - mbio, 2021 - Am Soc Microbiol
Herpes simplex viruses (HSV-1 and HSV-2) encode up to 16 envelope proteins, four of which
are essential for entry. However, whether these four proteins alone are sufficient to dictate …
are essential for entry. However, whether these four proteins alone are sufficient to dictate …
Murine cytomegalovirus deubiquitinase regulates viral chemokine levels to control inflammation and pathogenesis
Maintaining control over inflammatory processes represents a paradox for viral pathogens.
Although many viruses induce host inflammatory responses to facilitate infection, control is …
Although many viruses induce host inflammatory responses to facilitate infection, control is …
Novel routes for cytomegalovirus diagnosis and treatment
AT Hilterbrand - 2017 - repositories.lib.utexas.edu
… To my mother, Laura Hilterbrand, for your love and continued support in all my efforts. Your
strength and perseverance through all that you have endured drives me to better myself each …
strength and perseverance through all that you have endured drives me to better myself each …
Observation of single-protein and DNA macromolecule collisions on ultramicroelectrodes
… Adam T. Hilterbrand for plasmid DNA and helpful discussion. JED acknowledges the
National Science Foundation Graduate Research Fellowship (Grant No. DGE-1110007). …
National Science Foundation Graduate Research Fellowship (Grant No. DGE-1110007). …
[HTML][HTML] CBDB: the codon bias database
A Hilterbrand, J Saelens, C Putonti - BMC bioinformatics, 2012 - Springer
Background In many genomes, a clear preference in the usage of particular codons exists.
The mechanisms that induce codon biases remain an open question; studies have attributed …
The mechanisms that induce codon biases remain an open question; studies have attributed …
Evaluation of 244,000 synthetic sequences reveals design principles to optimize translation in Escherichia coli
Comparative analyses of natural and mutated sequences have been used to probe mechanisms
of gene expression, but small sample sizes may produce biased outcomes. We applied …
of gene expression, but small sample sizes may produce biased outcomes. We applied …