[HTML][HTML] STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway

…, F Sternberg, EE Pohl, C Sternberg, A Varady… - Molecular Cancer, 2023 - Springer
Prostate cancer (PCa) is a common and fatal type of cancer in men. Metastatic PCa (mPCa)
is a major factor contributing to its lethality, although the mechanisms remain poorly …

In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and …

L Gao, JCM Meiring, A Varady, IE Ruider… - Journal of the …, 2022 - ACS Publications
Photoswitchable reagents are powerful tools for high-precision studies in cell biology. When
these reagents are globally administered yet locally photoactivated in two-dimensional (2D) …

Thyroid and androgen receptor signaling are antagonized by μ‐crystallin in prostate cancer

…, M Schlederer, T Balber, A Varady… - … journal of cancer, 2021 - Wiley Online Library
Androgen deprivation therapy (ADT) remains a key approach in the treatment of prostate
cancer (PCa). However, PCa inevitably relapses and becomes ADT resistant. Besides …

[HTML][HTML] Non-neuromodulatory optogenetic tools in zebrafish

A Varady, M Distel - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
The zebrafish (Danio rerio) is a popular vertebrate model organism to investigate molecular
mechanisms driving development and disease. Due to its transparency at embryonic and …

Photocaged Hoechst Enables Subnuclear Visualization and Cell Selective Staining of DNA in vivo

CA Lämmle, A Varady, TG Müller, C Sturtzel… - …, 2021 - Wiley Online Library
Selective targeting of DNA by means of fluorescent labeling has become a mainstay in the
life sciences. While genetic engineering serves as a powerful technique and allows the …

STAT3 restricts prostate cancer metastasis and antiandrogen resistance by controlling LKB1/CREB signaling pathway

…, S Tangermann, I Hermanova, G Schäfer, A Varady… - bioRxiv, 2022 - biorxiv.org
Prostate cancer (PCa) lethality is driven by its progression to a metastatic castration-resistant
state, yet the signaling mechanisms underlying metastatic spread remain unknown. Here …

Image-guided intra-articular hip injections and risk of infection after hip arthroscopy

NH Varady, TB Amen, PF Abraham… - … American Journal of …, 2021 - journals.sagepub.com
Background: Although intra-articular injections are important in the management of patients
who may later undergo hip arthroscopy, conflicting data are available regarding the safety of …

[HTML][HTML] Osteoarthritis year in review 2015: mechanics

NH Varady, AJ Grodzinsky - Osteoarthritis and cartilage, 2016 - Elsevier
Motivated by the conceptual framework of multi-scale biomechanics, this narrative review
highlights recent major advances with a focus on gait and joint kinematics, then tissue-level …

[PDF][PDF] Moving Forward from Vulnerability to Adaptation

RG Varady, GM Garfin, R Beaty, L Brito… - 2012 - researchgate.net
Español/Hermosillo, Sonora representa un caso ilustrativo de crecimiento urbano en un
contexto de baja disponibilidad o disminución de agua, misma que tiende a agravarse por el …

Effect of Interfacial Regions and Surface Functional Groups on Chemical Transport in Polymer–Particle Composites

…, BA Mantooth, TP Pearl, MJ Varady - The Journal of …, 2023 - ACS Publications
Improved chemical resistance of polymer-based composites such as coatings remains a
significant challenge for many defense applications and technologies. In particular, composites …