T cell receptors (TCRs) enable T cells to specifically recognize mutations in cancer cells 1 ,
2 – 3 . Here we developed a clinical-grade approach based on CRISPR–Cas9 non-viral …

Tissue-resident lymphoid cells (TLCs) span the spectrum of innate-to-adaptive immune
function. Unlike traditional, circulating lymphocytes that are continuously generated from …

Highlights • Loss of IL7Rα resulted in significantly fewer eosinophils in adult mice. • IL7R-Cre
lineage tracing revealed minimal labeling of eosinophils. • IL7Rα-deficient HSCs robustly …

Background NeoTCR-P1 is a personalized autologous T cell therapy for treatment of patients
with solid tumors. Neoantigen-specific T cell receptors (neoTCRs) were isolated from the …

Traditional, adult-derived lymphocytes that circulate provide adaptive immunity to infection
and pathogens. However, subsets of lymphoid cells are also found in non-lymphoid tissues …

The current study was designed to synthesize biaryls compounds viz; 2-(3,4-difluorophenyl)
benzothiophene (DFPBT), 3-(3,4-difluorophenyl) quinoline (DFPQ) and 1-(3,4-difluorophenyl…

Aim of this paper is to investigate the relationship among information system of digital
banking, trust and customer satisfaction. For this we have applied the [1], SJ (2009) model to …

This study analyzed the institutional factors influencing sustainability of agricultural development
programme in Adamawa State, Nigeria. A multistage sampling technique was used to …

Maintenance after allogeneic hematopoietic cell transplantation (alloHCT) with hypomethylating
agents has yielded conflicting results. We conducted a single center retrospective …

There are many technologies associated with optical fiber sensing (OFS) and depending
upon the type of application, a specific OFS technology plays a crucial role in the associated …