Modulation of chromatin structure via histone modification is a major epigenetic mechanism
and regulator of gene expression. However, the contribution of chromatin features to tumor …

The persistence of cancer cells resistant to therapy remains a major clinical challenge. In
triple-negative breast cancer, resistance to chemotherapy results in the highest recurrence risk …

CD44 is a transmembrane glycoprotein linked to various biological processes reliant on
epigenetic plasticity, which include development, inflammation, immune responses, wound …

Objective Network meta-analysis was used to derive estimates of the relative efficacy of
inclisiran, evolocumab, alirocumab, bempedoic acid, and ezetimibe in patients with …

It was recently reported that the recBC mutants of Escherichia coli, deficient for DNA double-strand
break (DSB) repair, have a decreased copy number of their terminus region. We …

Background The treatment landscape for advanced non-small cell lung cancer (aNSCLC)
has evolved rapidly since immuno-oncology (IO) therapies were introduced. This study used …

Diffusion in the CoCrFeMnNi high-entropy alloy is investigated using an augmented tracer /
interdiffusion couple approach. The tracer diffusion coefficients are measured along the …

In the present series of papers, we describe the results of a systematic study on the anchoring
of cholesterol-tagged oligonucleotides to phospholipids bilayers followed by membrane-…

Specimens produced from technically pure iron and two different heats of ferritic/martensitic
steel T91 are investigated after exposure to oxygen-containing flowing lead–bismuth …

Marker frequency analysis of the Escherichia coli recB mutant chromosome has revealed a
deficit of DNA in a specific zone of the terminus, centred on the dif/TerC region. Using …