Bacteria can be genetically engineered to kill specific pathogens or inhibit their virulence.
We previously developed a synthetic genetic system that allows a laboratory strain of …

Fatty aldehydes and alcohols are valuable precursors used in the industrial manufacturing of
a myriad of specialty products. Herein, we demonstrate the de novo production of odd chain…

The effectiveness of virtual reality (VR) for learning and training is rooted in its ability to
create immersive and interactive environments that simulate real-world experiences. VR was …

Environmental pH is a fundamental signal continuously directing the metabolism and behavior
of living cells. Programming the precise cellular response toward environmental pH is, …

Chromosome-level design-build-test-learn cycles (chrDBTLs) allow systematic combinatorial
reconfiguration of chromosomes with ease. Here, we established chrDBTL with a …

Monoterpenoids are an important class of natural products that are derived from the condensation
of two five‑carbon isoprene subunits. They are widely used for flavouring, fragrances, …

Itaconic acid (IA) is a high-value organic acid with a plethora of industrial applications. In
this study, we seek to develop a microbial cell factory that could utilize waste cooking oil (WCO) …

Establishing efficient synthetic pathways for microbial production of biochemicals is often
hampered by competing pathways and insufficient precursor supply. Compartmentalization in …

Background Gene regulation in biological systems is impacted by the cellular and genetic
context-dependent effects of the biological parts which comprise the circuit. Here, we have …

Limonene is a valuable monoterpene widely used in the food and pharmaceutical industries.
Previously, we successfully engineered Yarrowia lipolytica to produce limonenes. In this …