Quantitative association between gene expression and blood cell production of individual hematopoietic stem cells in mice
…, AY Chowdhury, A Nogalska, J Contreras, Y Lee… - Science …, 2024 - science.org
Individual hematopoietic stem cells (HSCs) produce different amounts of blood cells upon
transplantation. Taking advantage of the intercellular variation, we developed an experimental …
transplantation. Taking advantage of the intercellular variation, we developed an experimental …
[PDF][PDF] Development of human alveolar epithelial cell models to study distal lung biology and disease
E Tran, T Shi, X Li, AY Chowdhury, D Jiang, Y Liu… - Iscience, 2022 - cell.com
Many acute and chronic diseases affect the distal lung alveoli. Alveolar epithelial cell (AEC)
lines are needed to better model these diseases. We used de-identified human remnant …
lines are needed to better model these diseases. We used de-identified human remnant …
Functional compensation between hematopoietic stem cell clones in vivo
L Nguyen, Z Wang, AY Chowdhury, E Chu… - EMBO …, 2018 - embopress.org
In most organ systems, regeneration is a coordinated effort that involves many stem cells,
but little is known about whether and how individual stem cells compensate for the …
but little is known about whether and how individual stem cells compensate for the …
[HTML][HTML] A role for prenylated rab acceptor 1 in vertebrate photoreceptor development
…, MI Othman, R Khanna, AJ Mears, AY Chowdhury… - BMC neuroscience, 2012 - Springer
Background The rd1 mouse retina is a well-studied model of retinal degeneration where rod
photoreceptors undergo cell death beginning at postnatal day (P) 10 until P21. This period …
photoreceptors undergo cell death beginning at postnatal day (P) 10 until P21. This period …
[HTML][HTML] Human pegivirus (GB virus C) NS3 protease activity inhibits induction of the type I interferon response and is not inhibited by HCV NS3 protease inhibitors
AY Chowdhury, JE Tavis, SL George - Virology, 2014 - Elsevier
We previously found that human pegivirus (HPgV; formerly GBV-C) NS3 protease activity
inhibits Human Immunodeficiency Virus (HIV) replication in a CD4+ T cell line. Given the …
inhibits Human Immunodeficiency Virus (HIV) replication in a CD4+ T cell line. Given the …
Development of novel in vitro human alveolar epithelial cell models to study distal lung biology and disease
E Tran, T Shi, X Li, AY Chowdhury, D Jiang, Y Liu… - Biorxiv, 2020 - biorxiv.org
Many acute and chronic lung diseases affect the distal lung alveoli. Although airway-derived
human cell lines exist, alveolar epithelial cell (AEC)-derived lines are needed to better …
human cell lines exist, alveolar epithelial cell (AEC)-derived lines are needed to better …
Functional Compensation Between Hematopoietic Stem Cells In Vivo
In most organ systems, regeneration is a coordinated effort that involves many stem cells,
but little is known about whether and how individual stem cells compensate for the functional …
but little is known about whether and how individual stem cells compensate for the functional …
[HTML][HTML] Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019
…, SG Choudhari, EK Chowdhury, FR Chowdhury… - The Lancet, 2022 - thelancet.com
Background Reducing the burden of death due to infection is an urgent global public health
priority. Previous studies have estimated the number of deaths associated with drug-…
priority. Previous studies have estimated the number of deaths associated with drug-…
Development of Novel Human Alveolar Epithelial Cell Models to Study Distal Lung Biology and Disease
…, T Shi, X Li, AY Chowdhury, D Jiang, Y Liu… - Available at SSRN … - papers.ssrn.com
Many acute and chronic lung diseases affect the distal lung alveoli. Although airway-derived
human cell lines exist, alveolar epithelial cell (AEC)-derived lines are needed to better …
human cell lines exist, alveolar epithelial cell (AEC)-derived lines are needed to better …
[HTML][HTML] Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
Smoking is a major heritable and modifiable risk factor for many diseases, including cancer,
common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have …
common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have …