[PDF][PDF] Early molecular layer interneuron hyperactivity triggers Purkinje neuron degeneration in SCA1

…, R Diab, XQ Ye, C Tietje, M Mounassir, A Odriozola… - Neuron, 2023 - cell.com
Toxic proteinaceous deposits and alterations in excitability and activity levels characterize
vulnerable neuronal populations in neurodegenerative diseases. Using in vivo two-photon …

[HTML][HTML] Synergistic interaction of sprouting and intussusceptive angiogenesis during zebrafish caudal vein plexus development

…, T Djukic, JD Kim, B Zuber, A Makanya, A Odriozola… - Scientific reports, 2018 - nature.com
Intussusceptive angiogenesis (IA) is a complementary method to sprouting angiogenesis (SA).
The hallmark of IA is formation of trans-capillary tissue pillars, their fusion and remodeling …

[HTML][HTML] PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD

…, A Schmitz, N Maharjan, R Diab, A Odriozola… - Acta …, 2022 - Springer
ER stress signaling is linked to the pathophysiological and clinical disease manifestations in
amyotrophic lateral sclerosis (ALS). Here, we have investigated ER stress-induced adaptive …

Capillary growth, ultrastructure remodelling and exercise training in skeletal muscle of essential hypertensive patients

…, R Buess, M Nyberg, H Hoppeler, A Odriozola… - Acta …, 2015 - Wiley Online Library
Aim The aim was to elucidate whether essential hypertension is associated with altered
capillary morphology and density and to what extent exercise training can normalize these …

Angiogenesis-related ultrastructural changes to capillaries in human skeletal muscle in response to endurance exercise

…, E Torchetti, C Malik, A Odriozola… - Journal of applied …, 2015 - journals.physiology.org
The ultrastructure of capillaries in skeletal muscle was morphometrically assessed in vastus
lateralis muscle (VL) biopsies taken before and after exercise from 22 participants of two …

Capillary ultrastructure and mitochondrial volume density in skeletal muscle in relation to reduced exercise capacity of patients with intermittent claudication

…, M Walker, PJ Walker, A Odriozola… - American journal …, 2016 - journals.physiology.org
Intermittent claudication (IC) is the most commonly reported symptom of peripheral arterial
disease (PAD). Impaired limb blood flow is a major casual factor of lower exercise tolerance in …

[HTML][HTML] Transluminal Pillars—Their Origin and Role in the Remodelling of the Zebrafish Caudal Vein Plexus

H Röss, D Aaldijk, M Vladymyrov, A Odriozola… - International journal of …, 2023 - mdpi.com
Intussusceptive pillars, regarded as a hallmark of intussusceptive angiogenesis, have been
described in developing vasculature of many organs and organisms. The aim of this study …

Wt1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium

…, A Sanz-Morejón, U Naumann, A Odriozola… - …, 2022 - journals.biologists.com
During development, the heart grows by addition of progenitor cells to the poles of the
primordial heart tube. In the zebrafish, Wilms tumor 1 transcription factor a (wt1a) and b (wt1b) …

[HTML][HTML] Multi-scale alignment of respiratory cilia and its relation to mucociliary function

M Schneiter, S Halm, A Odriozola, H Mogel… - Journal of structural …, 2021 - Elsevier
The tracheobronchial tree is lined by a mucociliary epithelium containing millions of multiciliated
cells. Their integrated oscillatory activity continuously propels an overlying pollution-…

[HTML][HTML] Structural microangiopathies in skeletal muscle related to systemic vascular pathologies in humans

O Baum, J Bernd, S Becker, A Odriozola… - Frontiers in …, 2020 - frontiersin.org
It is unclear how microangiopathic changes in skeletal muscle vary among systemic vascular
pathologies. We therefore analyzed the capillary fine structure in skeletal muscle from …