Constructing a minimal machinery for autonomous self-division of synthetic cells is a major
goal of bottom-up synthetic biology. One paradigm has been the E. coli divisome, with the …

Achieving autonomous motion is a central objective in designing artificial cells that mimic
biological cells in form and function. Cellular motion often involves complex multiprotein …

Liquid–liquid phase separation is a fundamental biophysical process to organize eukaryotic
and prokaryotic cytosols. While many biomolecular condensates are formed in the vicinity of…

FtsZ is a key component in bacterial cell division, being the primary protein of the presumably
contractile Z ring. In vivo and in vitro, it shows two distinctive features that could so far, …

The geometry of reaction compartments can affect the local outcome of interface‐restricted
reactions. Giant unilamellar vesicles (GUVs) are commonly used to generate cell‐sized, …

The bottom‐up reconstitution of proteins for their modular engineering into synthetic cellular
systems can reveal hidden protein functions in vitro. This is particularly evident for the …

Self-organized protein patterns are of tremendous importance for biological decision-making
processes. Protein patterns have been shown to identify the site of future cell division, …

In most bacteria, division depends on a cytoskeletal structure, the Z ring, which serves as a
scaffold for recruiting additional proteins, with which it forms the machinery responsible for …

FtsZ is a key component in bacterial cell division, being the primary protein of the 15 presumably
contractile Z ring. In vivo and in vitro, it shows two distinctive features that could 16 so …

Synthetic biology aims at the understanding of living organisms through an engineering
perspective, with the goal of improving or creating new biological systems. The prospect of …