User profiles for Adrian V. Cioanca
AV CioancaPostdoctoral fellow, Clear Vision Research, Australian National University Verified email at anu.edu.au Cited by 196 |
[HTML][HTML] Small-medium extracellular vesicles and their miRNA cargo in retinal health and degeneration: mediators of homeostasis, and vehicles for targeted gene …
Photoreceptor cell death and inflammation are known to occur progressively in retinal
degenerative diseases such as age-related macular degeneration (AMD). However, the molecular …
degenerative diseases such as age-related macular degeneration (AMD). However, the molecular …
[HTML][HTML] Short exposure to photo-oxidative damage triggers molecular signals indicative of early retinal degeneration
Introduction Age-related macular degeneration (AMD) is the leading cause of blindness in
the developed world, currently affecting over 350 billion people globally. For the most …
the developed world, currently affecting over 350 billion people globally. For the most …
The multifunctional human ocular melanocortin system
CLS Wu, AV Cioanca, MC Gelmi, L Wen… - Progress in Retinal and …, 2023 - Elsevier
Immune privilege in the eye involves physical barriers, immune regulation and secreted
proteins that together limit the damaging effects of intraocular immune responses and …
proteins that together limit the damaging effects of intraocular immune responses and …
[HTML][HTML] Impairing Gasdermin D-mediated pyroptosis is protective against retinal degeneration
Background Inflammasome activation and the subsequent release of pro-inflammatory
cytokines including Interleukin 1β (IL-1β) have been widely reported to contribute to the …
cytokines including Interleukin 1β (IL-1β) have been widely reported to contribute to the …
Extracellular matrix and oxidative stress regulate human retinal pigment epithelium growth
SS Eamegdool, EI Sitiwin, AV Cioanca… - Free Radical Biology and …, 2020 - Elsevier
Age-related macular degeneration (AMD), the most common cause of vision loss with ageing,
is characterised by degeneration of the photoreceptors and retinal pigment epithelium (…
is characterised by degeneration of the photoreceptors and retinal pigment epithelium (…
[HTML][HTML] Inhibition of microRNA-155 protects retinal function through attenuation of inflammation in retinal degeneration
Although extensively investigated in inflammatory conditions, the role of pro-inflammatory
microRNAs (miRNAs), miR-155 and miR-146a, has not been well-studied in retinal …
microRNAs (miRNAs), miR-155 and miR-146a, has not been well-studied in retinal …
Decrease in plasma miR-27a and miR-221 after concussion in Australian football players
Introduction: Sports-related concussion (SRC) is a common form of brain injury that lacks
reliable methods to guide clinical decisions. MicroRNAs (miRNAs) can influence biological …
reliable methods to guide clinical decisions. MicroRNAs (miRNAs) can influence biological …
[HTML][HTML] Functional microRNA targetome undergoes degeneration-induced shift in the retina
Background MicroRNA (miRNA) play a significant role in the pathogenesis of complex
neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-…
neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-…
[HTML][HTML] MicroRNA-223 regulates retinal function and inflammation in the healthy and degenerating retina
…, C Dietrich, R Aggio-Bruce, AV Cioanca… - Frontiers in Cell and …, 2020 - frontiersin.org
Introduction MicroRNAs (miRNAs) are small, non-coding RNA molecules that have powerful
regulatory properties, with the ability to regulate multiple messenger RNAs (mRNAs) and …
regulatory properties, with the ability to regulate multiple messenger RNAs (mRNAs) and …
The role of melanocytes in the human choroidal microenvironment and inflammation: insights from the transcriptome
The choroid within the human eye contains a rich milieu of cells including melanocytes.
Human choroidal melanocytes (HCMs) absorb light, regulate free radical production, and were …
Human choroidal melanocytes (HCMs) absorb light, regulate free radical production, and were …