Cas9/gRNA-mediated gene-drive systems have advanced development of genetic
technologies for controlling vector-borne pathogen transmission. These technologies include …

Resistance in Anopheles gambiae to members of all 4 major classes (pyrethroids, carbamates,
organochlorines, and organophosphates) of public health insecticides limits effective …

Background The mosquito Anopheles stephensi is a vector of urban malaria in Asia that
recently invaded Africa. Studying the genetic basis of vectorial capacity and engineering genetic …

Fenazaquin, pyridaben, tolfenpyrad and fenpyroximate are Complex I inhibitors offering a
new mode of action for insecticidal malaria vector control. However, extended exposure to …

The ability to manipulate the Anopheles gambiae genome and alter gene expression
effectively and reproducibly is a prerequisite for functional genetic analysis and for the …

Highlights • Advanced tools and resources are available to silence or overexpress Anopheles
genes. • Precise genome editing is broadly applicable to multiple Anopheles species. • …

The bipartite GAL4-UAS system is a versatile and powerful tool for functional genetic
analysis. The essence of the system is to cross transgenic 'driver' lines that express the yeast …

Functional genomic analysis and related strategies for genetic control of malaria rely on
validated and reproducible methods to accurately modify the genome of Anopheles mosquitoes. …

Due to a labeling error in one of our Iso-Seq samples, the RNA sample that was collected
24h after blood feeding was labeled as 324 by the sequencing center because they …

Anopheles stephensi is a vector of urban malaria in Asia and has recently invaded eastern
Africa. Genomic tools for studying its vectorial capacity and engineering genetic interventions …