Objective There is strong evidence for an involvement of different classes of non-coding RNAs,
including microRNAs and long non-coding RNAs, in the regulation of β-cell activities and …

Fine-tuning of insulin release from pancreatic β-cells is essential to maintain blood glucose
homeostasis. Here, we report that insulin secretion is regulated by a circular RNA containing …

Glucose-induced insulin secretion is an essential function of pancreatic β-cells that is partially
lost in individuals affected by Type 2 diabetes. This unique property of β-cells is acquired …

Maternal low-protein diets (LP) impair pancreatic β-cell development, resulting in later-life
failure and susceptibility to type 2 diabetes (T2D). We hypothesized that intrauterine and/or …

tRNA-derived fragments (tRFs) are an emerging class of small non-coding RNAs with distinct
cellular functions. Here, we studied the contribution of tRFs to the regulation of postnatal β …

Aims/hypothesis Evidence continues to emerge detailing a fine-tuning of the regulation of
metabolic processes and energy homeostasis by cell-autonomous circadian clocks. …

Objective To determine the frequency, type, and severity of adverse events (AEs) during
intrahospital transport of newborn infants and to identify associated factors. Study design We …

Glucose-induced insulin secretion, a hallmark of mature β-cells, is achieved after birth and is
preceded by a phase of intense proliferation. These events occurring in the neonatal period …

Worldwide researchers have invested time, effort, and money during the last years to find
new genes associated with diabetes susceptibility, such as LOC387761, HHEX, EXT2, and …

The discovery that most mammalian genome sequences are transcribed to RNA has
revolutionized our understanding of the mechanisms governing key cellular processes and of the …