User profiles for Advitiya Mahajan

Advitiya Mahajan

Student, University of Minnesota
Verified email at umn.edu
Cited by 112

[HTML][HTML] Smooth muscle cell-specific Notch1 haploinsufficiency restricts the progression of abdominal aortic aneurysm by modulating CTGF expression

J Sachdeva, A Mahajan, J Cheng, JT Baeten, B Lilly… - PloS one, 2017 - journals.plos.org
Aims Infiltration of macrophages and apoptosis of vascular smooth muscle cells (VSMCs)
promote the development of abdominal aortic aneurysm (AAA). Previously, we demonstrated …

Water-soluble luminescent silicon nanocrystals by plasma-induced acrylic acid grafting and PEGylation

Z Li, A Mahajan, HP Andaraarachchi… - ACS applied bio …, 2021 - ACS Publications
Luminescent silicon nanocrystals are promising nanomaterials for biomedical applications
due to their unique optical properties and biocompatibility. Here, we demonstrate a two-step …

[HTML][HTML] Transcriptomics analysis reveals new insights into the roles of Notch1 signaling on macrophage polarization

…, S Sen, S Zeng, R Dev, Y Jiang, A Mahajan… - Scientific reports, 2019 - nature.com
Naïve macrophages (Mφ) polarize in response to various environmental cues to a spectrum
of cells that have distinct biological functions. The extreme ends of the spectrum are …

Collagen fibril abnormalities in human and mice abdominal aortic aneurysm

…, A Debski, B Albert, DA Yeung, N Gadde, A Mahajan… - Acta biomaterialia, 2020 - Elsevier
Vascular diseases like abdominal aortic aneurysms (AAA) are characterized by a drastic
remodeling of the vessel wall, accompanied with changes in the elastin and collagen content. …

Physicochemical mechanisms of protection offered by agarose encapsulation during cryopreservation of mammalian cells in the absence of membrane-penetrating …

M Wang, A Mahajan, JS Miller… - ACS applied bio …, 2023 - ACS Publications
During freeze/thaw, cells are exposed to mechanical, thermal, chemical, and osmotic
stresses, which cause loss of viability and function. Cryopreservation agents such as dimethyl …

[HTML][HTML] Dextranol: An inert xeroprotectant

BJ Jones, A Mahajan, A Aksan - PloS one, 2019 - journals.plos.org
Dextranol, a reduced dextran, prevents damage to stored dry protein samples that
unmodified dextran would otherwise cause. Desiccation protectants (xeroprotectants) like the …

Dextranol: A better lyoprotectant

B Jones, A Mahajan, A Aksan - bioRxiv, 2018 - biorxiv.org
Dextranol, a reduced dextran, prevents damage to stored dry protein samples that unmodified
dextran would otherwise cause. Lyoprotectants like the polysaccharide dextran are critical …

Notch Inhibition Reverses the Polarization of Pro-Inflammatory (M1) to Anti-Inflammatory-like (M2) Macrophages

R Dev, A Mahajan, N Sharma… - … Thrombosis, and Vascular …, 2018 - Am Heart Assoc
Introduction: Our previous studies demonstrated that loss of Notch1 signaling reduces the
incidence of abdominal aortic aneurysm (AAA) by preventing the influx of pro-inflammatory M1 …

Use of Machine Learning to Predict the Desiccation Tolerance of Bacteria

MLC Clipsham - 2021 - search.proquest.com
For efficient long-term storage and use of bacteria for environmental applications,
understanding and identifying desiccation resistance in bacteria is key. In the past, desiccation …

Development of silica-based physical confinement models to isolate and study dormancy-prone cancer cells

JA Preciado - 2021 - search.proquest.com
Metastatic cancers account for the majority of cancer-related deaths. Some metastatic tumors
arise after a latent, disease-free period. The latency is attributed to cancer cells being in a …