Emodin is a component in a Chinese herb, Rheum officinale Baill, traditionally used for
diabetes and anticancer. Its poor solubility is one of the major challenges to pharmaceutical …

Fibronectin (FN), a large heterodimeric glycoprotein, can be found in soluble form in plasma
or in insoluble form as an extracellular matrix protein. Cellular FN is produced by various …

Emodin (EM), an anthraquinone obtained from natural products, is known for many
pharmacological activities. However, further evaluation and interpretation of toxicity or …

Diabetic foot ulcers represent one of the major and rising health issues, as the number of
diabetic patients is increasing. MicroRNAs (miRNAs) are among various bioactive molecules …

Histone H3K4me1 and H3K27ac are enhancer‐specific modifications and are required for
enhancers to activate transcription of target genes. However, the reciprocal effects of these …

The symbiotic microbiota profoundly affect many aspects of host physiology; however, the
molecular mechanisms underlying host-microbe cross-talk are largely unknown. Here, we …

Although linearly distant along mouse chromosome 7 and human chromosome 11, the
mammalian β-globin gene is located in close proximity to the upstream locus control region …

Aims Invasive breast carcinoma ( IBC ) with neuroendocrine ( NE ) differentiation has been
controversial in terms of its definition and clinical outcome. We investigated the incidence and …

The establishment of epigenetic marks, such as methylation on histone tails, is mechanistically
linked to RNA polymerase II within active genes. To explore the interplay between these …

Coacervation is a liquid–liquid phase separation that can occur in solutions of macromolecules
through self-assembly or electrostatic interactions. Recently, coacervates composed of …