User profiles for Ahmed Sayadi

ahmed sayadi

Bioinformatics Research, Uppsala university
Verified email at ebc.uu.se
Cited by 1069

ELM: the status of the 2010 eukaryotic linear motif resource

…, S Michael, A Sayadi… - Nucleic acids …, 2010 - academic.oup.com
Linear motifs are short segments of multidomain proteins that provide regulatory functions
independently of protein tertiary structure. Much of intracellular signalling passes through …

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

…, M Ali, I Krystkowiak, L Simonetti, A Sayadi… - Molecular Systems …, 2022 - embopress.org
Specific protein–protein interactions are central to all processes that underlie cell physiology.
Numerous studies have together identified hundreds of thousands of human protein–…

[HTML][HTML] The De Novo Transcriptome and Its Functional Annotation in the Seed Beetle Callosobruchus maculatus

A Sayadi, E Immonen, H Bayram, G Arnqvist - PLoS One, 2016 - journals.plos.org
Despite their unparalleled biodiversity, the genomic resources available for beetles (Coleoptera)
remain relatively scarce. We present an integrative and high quality annotated …

[HTML][HTML] Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

…, F Mihalic, F Coscia, R Inturi, A Sayadi… - Nature …, 2021 - nature.com
Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host
factors. However, most current large-scale methods do not identify this important class of …

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

EA Bard-Chapeau, AT Nguyen, AG Rust, A Sayadi… - Nature …, 2014 - nature.com
The most common risk factor for developing hepatocellular carcinoma (HCC) is chronic
infection with hepatitis B virus (HBV). To better understand the evolutionary forces driving HCC, …

[PDF][PDF] Application of TOPSIS method for selecting the most appropriate blast design

…, H Dehghani, TN Singh, AR Sayadi… - Arabian journal of …, 2012 - academia.edu
Blasting operation should be performed satisfying some criteria, such as fragmentation,
flyrock, and cost. To reach the most appropriate alternative among previous performed blast …

[HTML][HTML] Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

…, R Inturi, M Ali, I Krystkowiak, A Sayadi… - Nature …, 2023 - nature.com
Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions.
Studies of motif-mediated interactions therefore provide insight into virus-host dependencies, …

[HTML][HTML] The genomic footprint of sexual conflict

A Sayadi, A Martinez Barrio, E Immonen… - Nature ecology & …, 2019 - nature.com
Genes with sex-biased expression show a number of unique properties and this has been
seen as evidence for conflicting selection pressures in males and females, forming a genetic ‘…

[HTML][HTML] Sexual conflict drives micro-and macroevolution of sexual dimorphism in immunity

…, I Martinossi-Allibert, J Baur, A Sayadi… - BMC biology, 2021 - Springer
Background Sexual dimorphism in immunity is believed to reflect sex differences in reproductive
strategies and trade-offs between competing life history demands. Sexual selection can …

A chromosome-level assembly of the seed beetle Callosobruchus maculatus genome with annotation of its repetitive elements

…, I Westerberg, J Galbraith, A Sayadi… - G3: Genes …, 2024 - academic.oup.com
Callosobruchus maculatus is a major agricultural pest of legume crops worldwide and an
established model system in ecology and evolution. Yet, current molecular biological …