Nucleic acids are the natural cargo of viruses and key determinants that affect viral shell
stability. In some cases the genome structurally reinforces the shell, whereas in others genome …

Sister chromatid cohesion requires cohesin to act as a protein linker to hold chromatids
together. How cohesin tethers chromatids remains poorly understood. We have used optical …

Vaults are ubiquitous ribonucleoprotein particles involved in a diversity of cellular processes,
with promising applications as nanodevices for delivery of multiple cargos. The vault shell …

Virus-like particles (VLPs) provide engineering platforms for the design and implementation
of protein-based nanostructures. These capsids are comprised of protein subunits whose …

… Michiel van de Waterbeemd,1,2 Aida Llauró,3 Joost Snijder,1,2 Alejandro Valbuena,4 Alicia
Rodrıguez-… Michiel van de Waterbeemd and Aida Llauró contributed equally to this work. …

Vaults are the largest ribonucleoprotein particles found in eukaryotic cells, with an unclear
cellular function and promising applications as vehicles for drug delivery. In this article, we …

Kinetochores are multiprotein machines that drive chromosome segregation by maintaining
persistent, load-bearing linkages between chromosomes and dynamic microtubule tips. …

Viral particles are endowed with physicochemical properties whose modulation confers
certain metastability to their structures to fulfill each task of the viral cycle. Here, we investigate …

Vault particles are naturally occurring proteinaceous cages with promising application as
molecular containers. The use of vaults as functional transporters requires a profound …

The capsid of P22 bacteriophage undergoes a series of structural transitions during
maturation that guide it from spherical to icosahedral morphology. The transitions include the …