For many decades, glucocorticoids have been widely used as the gold standard treatment
for inflammatory conditions. Unfortunately, their clinical use is limited by severe adverse …

Glucocorticoids (GCs) are effective anti-inflammatory drugs; yet, their mechanisms of action
are poorly understood. GCs bind to the glucocorticoid receptor (GR), a ligand-gated …

Glucocorticoids are potent anti-inflammatory drugs; however, their molecular mode of action
remains complex and elusive. They bind to the glucocorticoid receptor (GR), a nuclear …

By performing whole-genome sequencing in a Swedish cohort of 71 parent-offspring trios,
in which the child in each family is affected by systemic lupus erythematosus (SLE, OMIM …

Glucocorticoids (such as Dexamethasone) are commonly used immunomodulatory drugs
with potent anti-inflammatory effects, whose mechanisms of action remain incompletely …

Quantifying differential genome occupancy by chromatin immunoprecipitation (ChIP) remains
challenging due to variation in chromatin fragmentation, immunoprecipitation efficiencies, …

Zusammenfassung Der Einsatz von Glukokortikoiden bilden den Goldstandard bei der
Behandlung zahlreicher entzündlicher Erkrankungen bis hin zu schweren Verläufen bei …

Glucocorticoids (GCs) are highly effective anti-inflammatory drugs, yet their mechanisms of
action are poorly understood. GCs bind to the glucocorticoid receptor (GR), a ligand gated …

Zusammenfassung Der Einsatz von Glukokortikoiden bilden den Goldstandard bei der
Behandlung zahlreicher entzündlicher Erkrankungen bis hin zu schweren Verläufen bei …

The Glucocorticoid Receptor (GR) is an important immunosuppressive and anti-inflammatory
drug target. It belongs to the nuclear receptor family of ligand-controlled transcription factors…