User profiles for Ajay Pillai

Ajay S. Pillai

Faculty Research Associate, Johns Hopkins School of Medicine
Verified email at jhmi.edu
Cited by 796

[HTML][HTML] Malaria parasite clag3 genes determine channel-mediated nutrient uptake by infected red blood cells

W Nguitragool, AAB Bokhari, AD Pillai, K Rayavara… - Cell, 2011 - cell.com
Development of malaria parasites within vertebrate erythrocytes requires nutrient uptake at
the host cell membrane. The plasmodial surface anion channel (PSAC) mediates this …

Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India

…, ASN Seshasayee, M Bhat, Y Shouche, A Pillai… - Science, 2021 - science.org
Delhi, the national capital of India, experienced multiple severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) outbreaks in 2020 and reached population seropositivity of >50…

Novel drug designing approach for dual inhibitors as anti-inflammatory agents: implication of pyridine template

AD Pillai, PD Rathod, PX Franklin, M Patel… - Biochemical and …, 2003 - Elsevier
Compounds incorporating thiophene moiety, a pi excess five membered heterocycle, have
attracted a great deal of research interest, owing to the therapeutic utility of the template as …

[PDF][PDF] The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations

…, R Smith, K Devlin, R Margolis, L Derr, A Lee, A Pillai - Cell systems, 2018 - cell.com
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common
Fund program that catalogs how human cells globally respond to chemical, genetic, and …

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response …

…, M Medvedovic, A Ma'ayan, A Pillai… - Nucleic acids …, 2018 - academic.oup.com
The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national
consortium funded by the NIH to generate a diverse and extensive reference library of cell-…

[HTML][HTML] Advancing biological understanding and therapeutics discovery with small-molecule probes

…, RN Margolis, E Michelotti, ME Perry, A Pillai… - Cell, 2015 - cell.com
Small-molecule probes can illuminate biological processes and aid in the assessment of
emerging therapeutic targets by perturbing biological systems in a manner distinct from other …

[HTML][HTML] Influence of cholesterol on cancer progression and therapy

SS Mayengbam, A Singh, AD Pillai, MK Bhat - Translational oncology, 2021 - Elsevier
Cholesterol is a fundamental molecule necessary for the maintenance of cell structure and
is vital to various normal biological functions. It is a key factor in lifestyle-related diseases …

[PDF][PDF] Symmetry breaking in space-time hierarchies shapes brain dynamics and behavior

AS Pillai, VK Jirsa - Neuron, 2017 - cell.com
In order to maintain brain function, neural activity needs to be tightly coordinated within the
brain network. How this coordination is achieved and related to behavior is largely unknown. …

Pharos 2023: an integrated resource for the understudied human proteome

…, J Holmes, KR Sharma, A Pillai… - Nucleic acids …, 2023 - academic.oup.com
The Illuminating the Druggable Genome (IDG) project aims to improve our understanding of
understudied proteins and our ability to study them in the context of disease biology by …

Use of 3-D printing technologies in craniomaxillofacial surgery: a review

…, Y Sharma, N Jain, M Satpathy, AK Pillai - Oral and maxillofacial …, 2018 - Springer
Three-dimensional (3-D) printing is a method of manufacturing in which materials like plastic
or metal are deposited onto one another in layers to produce a 3-D object. Because of the …