User profiles for Akeel Abo Alard

Akeel Abo Alard

Faculty of Pharmacy/ University of Kufa
Verified email at uokufa.edu.iq
Cited by 205

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B

AF Zyryanova, F Weis, A Faille, AA Alard… - Science, 2018 - science.org
The integrated stress response (ISR) is a conserved translational and transcriptional
program affecting metabolism, memory, and immunity. The ISR is mediated by stress-induced …

[HTML][HTML] Design, synthesis, docking study and preliminary pharmacological assessment of new norfloxacin analogues having thiazole nucleus

NT Ajjah, NH Naser, AAA Alard… - Journal of Biochemical …, 2020 - jbiochemtech.com
Design, Synthesis, Docking Study and Preliminary Pharmacological Assessment of New
Norfloxacin Analogues Having Thiazole Nucleus - Journal Of Biochemical Technology Journal …

[PDF][PDF] Design, Synthesis and Pharmacological Evaluation of New Lomefloxacin Derivatives Having Oxadiazole Nucleus

AR Saeed, NH Naser, AAA Alard - Journal of Pharmaceutical …, 2019 - researchgate.net
Infectious diseases are accompanied by inflammation as a defense mechanism through the
role of arachidonic acid cascade or cyclooxygenase enzyme. Many researches indicated …

Binding of the integrated stress response inhibitor, ISRIB, reveals a regulatory site in the nucleotide exchange factor, elF2B

AF Zyryanova, F Weis, A Faille, A Abo Alard… - bioRxiv, 2017 - biorxiv.org
The Integrated Stress Response (ISR) is a conserved eukaryotic translational and
transcriptional program implicated in mammalian metabolism, memory and immunity. The ISR is …

Design, Synthesis and Disposition Studies of New ISRIB Analogues, Targeting eIF2B, as Potential Candidates for enhancing protein synthesis rate

A Abo Alard - 2021 - eprints.nottingham.ac.uk
Neurodegenerative diseases represent a major cause of dementia, which is predominantly
a disease of the elderly, and is characterised by a decline in cognitive functions and memory. …

[HTML][HTML] Trust your gut: the association of gut microbiota and liver disease

…, M Memon, M Yasin, H Memon, M Rustom, M Al Akeel… - Microorganisms, 2022 - mdpi.com
The gut microbiota composition is important for nutrient metabolism, mucosal barrier function,
immunomodulation, and defense against pathogens. Alterations in the gut microbiome can …

[HTML][HTML] Insights on the structural and metabolic resistance of potato (Solanum tuberosum) cultivars to tuber black dot (Colletotrichum coccodes)

J Massana-Codina, S Schnee, PM Allard… - Frontiers in plant …, 2020 - frontiersin.org
Black dot is a blemish disease of potato tubers caused by the phytopathogenic fungus
Colletotrichum coccodes. Qualitative resistance (monogenic) that leads to the hypersensitive …

[PDF][PDF] 1.3 The IIHE team in 2018

JA AGUILAR, HBPI until April, K CMS, J Auger… - Interuniversity Institue for … - iihe.ac.be
… Shimaa ABU ZEID ERASMUS MUNDOS (PhD student) CMS Aqeel AHMED EOS scientific
collaborator (post-doc) since October Pheno Freya BLEKMAN ZAP hoofddocent CMS …

[HTML][HTML] 27th Annual GP2A Medicinal Chemistry Conference

SN Mistry, P Marchand, B Kellam - 2019 - mdpi.com
The 27th annual GP2A (Groupement des Pharmacochimistes de l′Arc Atlantique/Group of
Medicinal Chemists in the Atlantic Arc) conference took place from 21 to 23 August 2019, at …

Meeting report: 27th Annual GP2A Medicinal Chemistry Conference

SN Mistry, P Marchand… - …, 2019 - nottingham-repository.worktribe.com
The 27th annual GP2A (Groupement des Pharmacochimistes de l?Arc Atlantique/Group of
Medicinal Chemists in the Atlantic Arc) conference took place from 21 to 23 August 2019, at …