Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non-European …

The overwhelming majority of participants in current genetic studies are of European ancestry.
To elucidate disease biology in the East Asian population, we conducted a genome-wide …

The predictive role of antinuclear antibodies (ANAs) remains elusive in the long‐term outcome
of primary biliary cirrhosis (PBC). The progression of PBC was evaluated in association …

We examined the effects of a stimulatory anti-beta 1 mAb (TS2/16) and different divalent cations
on VLA-4-mediated cell adhesion to vascular cell adhesion molecule-1 (VCAM-1), to the …

Background REACH evaluated ramucirumab in the second-line treatment of patients with
advanced hepatocellular carcinoma. In the intent-to-treat population (n = 565), a significant …

To investigate the role of β1 integrins in pancreatic carcinoma invasion, we analyzed the
relationship between the activity of β1 integrins and the invasive ability of human pancreatic …

To investigate the role of integrins in hepatocellular carcinoma (HCC) invasion, we analyzed
the relationship between the expression and activity of β1 integrins and the invasive ability …

Hunner-type interstitial cystitis (HIC) is a rare, chronic inflammatory disease of the urinary
bladder with unknown etiology and genetic background. Here, we conduct a genome-wide …

Atezolizumab plus bevacizumab and lenvatinib are approved frontline therapies for advanced
hepatocellular carcinoma (HCC). Patients with advanced HCC continue to have a poor …

The current genome-wide association studies (GWASs) do not yet capture sufficient diversity
in terms of populations and scope of phenotypes. To address an essential need to expand …