Oligodendrocyte precursor cells (OPCs) in the adult brain contribute to white matter
homeostasis. After white matter damage, OPCs compensate for oligodendrocyte loss by …

Inflammation is crucially involved in the development of carotid plaques. We examined the
relationship between plaque vulnerability and inflammatory biomarkers using intraoperative …

Background and Purpose— Pentraxin 3 (PTX3) is released on inflammatory responses in
many organs. However, roles of PTX3 in brain are still mostly unknown. Here we asked …

Oligodendrocytes are one of the major cell types in cerebral white matter. Under normal
conditions, they form myelin sheaths that encircle axons to support fast nerve conduction. Under …

Pericytes are embedded within basal lamina and play multiple roles in the perivascular
niche in brain. Recently, oligodendrocyte precursor cells (OPCs) have also been reported to …

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
(CARASIL) is clinically characterized by early-onset dementia, stroke, spondylosis …

Background The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), began in late 2019. One of the vaccines …

Vascular cognitive impairment (VCI) refers to all forms of cognitive disorder related to
cerebrovascular diseases, including vascular mild cognitive impairment, post-stroke dementia, multi…

BACKGROUND AND PURPOSE Cortical microinfarcts (CMIs) are detected as small foci
restricted to the cerebral cortex in autopsy brains. CMIs are thought to be caused by cerebral …

Cerebral small vessel disease (SVD) refers to a group of disease conditions affecting the
cerebral small vessels, which include the small arteries, arterioles, capillaries, and …