Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans
…, AR Krebs, D Schübeler, RI Hajdu, A Lukats… - Nature …, 2019 - nature.com
Targeting genes to specific neuronal or glial cell types is valuable for both understanding
and repairing brain circuits. Adeno-associated viruses (AAVs) are frequently used for gene …
and repairing brain circuits. Adeno-associated viruses (AAVs) are frequently used for gene …
[HTML][HTML] Pathologic alterations of the outer retina in streptozotocin-induced diabetes
Purpose.: Neurodegeneration as an early event of diabetic retinopathy preceding clinically
detectable vascular alterations is a widely proven issue today. While there is evidence for the …
detectable vascular alterations is a widely proven issue today. While there is evidence for the …
Photoreceptor distribution in the retinas of subprimate mammals
Á Szél, Á Lukáts, T Fekete, Z Szepessy, P Röhlich - JOSA A, 2000 - opg.optica.org
Relevant data on the distribution of color cones are summarized, with special emphasis on
the marked dorso–ventral asymmetries observed in a number of mammalian species. In …
the marked dorso–ventral asymmetries observed in a number of mammalian species. In …
[HTML][HTML] Histological evaluation of diabetic neurodegeneration in the retina of Zucker diabetic fatty (ZDF) rats
In diabetes, retinal dysfunctions exist prior to clinically detectable vasculopathy, however the
pathology behind these functional deficits is still not fully established. Previously, our group …
pathology behind these functional deficits is still not fully established. Previously, our group …
Characterization of connexin36 gap junctions in the human outer retina
Retinal connexins (Cx) form gap junctions (GJ) in key circuits that transmit average or
synchronize signals. Expression of Cx36, -45, -50 and -57 have been described in many species …
synchronize signals. Expression of Cx36, -45, -50 and -57 have been described in many species …
Bipolar cell gap junctions serve major signaling pathways in the human retina
…, R Nitschke, A Naumann, A Énzsöly, Á Lukáts… - Brain Structure and …, 2017 - Springer
Connexin36 (Cx36) constituent gap junctions (GJ) throughout the brain connect neurons into
functional syncytia. In the retina they underlie the transmission, averaging and correlation …
functional syncytia. In the retina they underlie the transmission, averaging and correlation …
[HTML][HTML] Visual pigment coexpression in all cones of two rodents, the Siberian hamster, and the pouched mouse
Á Lukáts, O Dkhissi-Benyahya, Z Szepessy… - … & visual science, 2002 - arvojournals.org
purpose. To decide whether the identical topography of short-and middle-wavelength cone
photoreceptors in two species of rodents reflects the presence of both opsins in all cone cells…
photoreceptors in two species of rodents reflects the presence of both opsins in all cone cells…
[HTML][HTML] In vivo and in vitro development of S-and M-cones in rat retina
…, A Szabó, G Pinzon-Duarte, Á Lukáts… - … & visual science, 2010 - arvojournals.org
Purpose.: Organ cultures of the rodent retina could provide a powerful tool in the study of
cone development and differentiation. Previous attempts, however, have failed to show M-cone …
cone development and differentiation. Previous attempts, however, have failed to show M-cone …
[HTML][HTML] The topography of rods, cones and intrinsically photosensitive retinal ganglion cells in the retinas of a nocturnal (Micaelamys namaquensis) and a diurnal …
I Van der Merwe, A Lukats, V Blahova… - PLoS …, 2018 - journals.plos.org
We used immunocytochemistry to determine the presence and topographical density
distributions of rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs) in the …
distributions of rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs) in the …
Novel features of neurodegeneration in the inner retina of early diabetic rats
The literature indicates that in diabetes retinal dysfunctions related to neural retinal alterations
exist prior to clinically detectable vasculopathy. In a previous report, a detailed description …
exist prior to clinically detectable vasculopathy. In a previous report, a detailed description …