Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

…, AR Krebs, D Schübeler, RI Hajdu, A Lukats… - Nature …, 2019 - nature.com
Targeting genes to specific neuronal or glial cell types is valuable for both understanding
and repairing brain circuits. Adeno-associated viruses (AAVs) are frequently used for gene …

[HTML][HTML] Pathologic alterations of the outer retina in streptozotocin-induced diabetes

…, K Szabó, Á Szél, J Németh, Á Lukáts - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: Neurodegeneration as an early event of diabetic retinopathy preceding clinically
detectable vascular alterations is a widely proven issue today. While there is evidence for the …

Photoreceptor distribution in the retinas of subprimate mammals

Á Szél, Á Lukáts, T Fekete, Z Szepessy, P Röhlich - JOSA A, 2000 - opg.optica.org
Relevant data on the distribution of color cones are summarized, with special emphasis on
the marked dorso–ventral asymmetries observed in a number of mammalian species. In …

[HTML][HTML] Histological evaluation of diabetic neurodegeneration in the retina of Zucker diabetic fatty (ZDF) rats

…, LK Laurik, GM Somfai, B Merkely, Á Szél, Á Lukáts - Scientific reports, 2017 - nature.com
In diabetes, retinal dysfunctions exist prior to clinically detectable vasculopathy, however the
pathology behind these functional deficits is still not fully established. Previously, our group …

Characterization of connexin36 gap junctions in the human outer retina

…, J Orbán, M Nyitrai, J Németh, Á Szél, Á Lukáts… - Brain Structure and …, 2016 - Springer
Retinal connexins (Cx) form gap junctions (GJ) in key circuits that transmit average or
synchronize signals. Expression of Cx36, -45, -50 and -57 have been described in many species …

Bipolar cell gap junctions serve major signaling pathways in the human retina

…, R Nitschke, A Naumann, A Énzsöly, Á Lukáts… - Brain Structure and …, 2017 - Springer
Connexin36 (Cx36) constituent gap junctions (GJ) throughout the brain connect neurons into
functional syncytia. In the retina they underlie the transmission, averaging and correlation …

[HTML][HTML] Visual pigment coexpression in all cones of two rodents, the Siberian hamster, and the pouched mouse

Á Lukáts, O Dkhissi-Benyahya, Z Szepessy… - … & visual science, 2002 - arvojournals.org
purpose. To decide whether the identical topography of short-and middle-wavelength cone
photoreceptors in two species of rodents reflects the presence of both opsins in all cone cells…

[HTML][HTML] In vivo and in vitro development of S-and M-cones in rat retina

…, A Szabó, G Pinzon-Duarte, Á Lukáts… - … & visual science, 2010 - arvojournals.org
Purpose.: Organ cultures of the rodent retina could provide a powerful tool in the study of
cone development and differentiation. Previous attempts, however, have failed to show M-cone …

[HTML][HTML] The topography of rods, cones and intrinsically photosensitive retinal ganglion cells in the retinas of a nocturnal (Micaelamys namaquensis) and a diurnal …

I Van der Merwe, A Lukats, V Blahova… - PLoS …, 2018 - journals.plos.org
We used immunocytochemistry to determine the presence and topographical density
distributions of rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs) in the …

Novel features of neurodegeneration in the inner retina of early diabetic rats

…, A Szabó, K Szabó, Á Szél, J Németh, Á Lukáts - 2015 - digitum.um.es
The literature indicates that in diabetes retinal dysfunctions related to neural retinal alterations
exist prior to clinically detectable vasculopathy. In a previous report, a detailed description …