Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive
loss of motor neurons in the CNS. Astrocytes play a critical role in disease progression …

Connexin 43 (Cx43) gap junctions and hemichannels mediate astrocyte intercellular
communication in the central nervous system under normal conditions and contribute to astrocyte-…

Mutations in TUBB4A result in a spectrum of leukodystrophy including Hypomyelination with
Atrophy of Basal Ganglia and Cerebellum (H-ABC), a rare hypomyelinating leukodystrophy, …

Therapeutic strategies using stem cells for treating neurological diseases are receiving more
attention as the scientific community appreciates cell-autonomous contributions to several …

Neural stem cells (NSCs) are being investigated as a possible treatment for amyotrophic
lateral sclerosis (ALS) through intraspinal transplantation, but no longitudinal imaging studies …

Spinal cord injury is a long-lasting, debilitating condition that affects 250,000 people in the
United States. Spontaneous functional recovery after human spinal cord injury is limited …

Mutations in tubulin alpha 4a (TUBB4A) result in a spectrum of leukodystrophies, including
Hypomyelination with atrophy of basal ganglia and cerebellum (H-ABC), resulting from a …

Connexin 43 (Cx43) gap junctions and hemichannels mediate astrocyte intercellular
communication in the central nervous system under normal conditions and may contribute to …

Oligodendrocytes (OLs) are particularly susceptible to the toxicity of the acute lesion environment
after spinal cord injury (SCI). They undergo both necrosis and apoptosis acutely, with …

Our understanding of astrocytes and their role in neurological diseases has increased
considerably over the past two decades as the diverse roles of these cells have become …