Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

…, J Bakker, F Girach, A Hellysaz, R Tomer, A Alpar… - Nature …, 2017 - nature.com
The hypothalamus contains the highest diversity of neurons in the brain. Many of these
neurons can co-release neurotransmitters and neuropeptides in a use-dependent manner. …

The renaissance of Ca2+-binding proteins in the nervous system: secretagogin takes center stage

A Alpár, J Attems, J Mulder, T Hökfelt, T Harkany - Cellular signalling, 2012 - Elsevier
Effective control of the Ca 2+ homeostasis in any living cell is paramount to coordinate
some of the most essential physiological processes, including cell division, morphological …

The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal

J Webster, C Urban, K Berbaum, C Loske, A Alpar… - Neurotoxicity …, 2005 - Springer
Advanced glycation end products (AGEs) have been identified in age-related intracellular
protein deposits of Alzheimer’s disease (amyloid plaques and neurofibrillary tangles) and …

Molecular reorganization of endocannabinoid signalling in Alzheimer's disease

J Mulder, M Zilberter, SJ Pasquare, A Alpar, G Schulte… - Brain, 2011 - academic.oup.com
Retrograde messengers adjust the precise timing of neurotransmitter release from the
presynapse, thus modulating synaptic efficacy and neuronal activity. 2-Arachidonoyl glycerol, an …

At the tip of an iceberg: prenatal marijuana and its possible relation to neuropsychiatric outcome in the offspring

A Alpár, V Di Marzo, T Harkany - Biological Psychiatry, 2016 - Elsevier
Endocannabinoids regulate brain development via modulating neural proliferation,
migration, and the differentiation of lineage-committed cells. In the fetal nervous system, (endo)…

Distribution of pyramidal cells associated with perineuronal nets in the neocortex of rat

A Alpár, U Gärtner, W Härtig, G Brückner - Brain research, 2006 - Elsevier
Perineuronal nets are lattice-like accumulations of extracellular matrix components around
the cell body and perisomatic portion of certain neurons. Whereas interneurons associated to …

[HTML][HTML] Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling

A Alpár, G Tortoriello, D Calvigioni, MJ Niphakis… - Nature …, 2014 - nature.com
Local environmental cues are indispensable for axonal growth and guidance during brain
circuit formation. Here, we combine genetic and pharmacological tools, as well as systems …

Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease

…, J Attems, H Tanila, T Arendt, T Harkany, A Alpár - Acta …, 2013 - Springer
Perineuronal matrix is an extracellular protein scaffold to shape neuronal responsiveness
and survival. Whilst perineuronal nets engulf the somatodendritic axis of neurons, axonal …

Development and surgical anatomy of the round window niche

M Tóth, A Alpár, L Patonay, I Oláh - Annals of Anatomy-Anatomischer …, 2006 - Elsevier
The round window niche is a bony pouch of the tympanic cavity and clinically frequently
explored, therefore its topography has fundamental impact on microsurgery. A total of 783 …

[HTML][HTML] A hypothalamic dopamine locus for psychostimulant-induced hyperlocomotion in mice

…, P Rebernik, M Pende, L Boi, A Alpár… - Nature …, 2022 - nature.com
The lateral septum (LS) has been implicated in the regulation of locomotion. Nevertheless,
the neurons synchronizing LS activity with the brain’s clock in the suprachiasmatic nucleus (…