Heart failure is characterized by a debilitating decline in cardiac function 1 , and recent
clinical trial results indicate that improving the contractility of heart muscle cells by boosting …

In the past few years, the use of specific cell types derived from induced pluripotent stem
cells (iPSCs) has developed into a powerful approach to investigate the cellular …

Heart failure (HF) is a leading cause of death worldwide. The most common conditions that
lead to HF are coronary artery disease, myocardial infarction, valve disorders, high blood …

Engineering native‐like myocardial muscle, recapitulating its fibrillar organization and
mechanical behavior is still a challenge. This study reports the rational design and fabrication of …

Objective— To improve regeneration of the injured myocardium, it is necessary to enhance
the intrinsic capacity of the heart to regenerate itself and/or replace the damaged tissue by …

Previous studies investigating the role of circulating microRNAs in acute coronary syndrome
(ACS) were based on small patient numbers, performed no comparison with established …

Modulating signaling pathways including Wnt and Hippo can induce cardiomyocyte proliferation
in vivo. Applying these signaling modulators to human induced pluripotent stem cell-…

Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease in the
Western population, claiming 17000 deaths per year in the United States and affecting 25% of …

Aims Angiogenesis is a critical component of many pathological conditions in adult tissues
and is essential for embryonic development. MicroRNAs are indispensable for normal …

To improve regeneration of the injured myocardium, cardiomyocyte progenitor cells (CMPCs)
have been put forward as a potential cell source for transplantation therapy. Although cell …