One of the most popular approaches for maintaining populations and conserving biodiversity
in fragmented landscapes is to retain or create corridors that connect otherwise isolated …

Within the Nile Delta gas province, reservoirs are dominated by Pliocene slope-channel
systems, which are spectacularly imaged on high-quality three-dimensional seismic data. This …

Source-related geochemical data define at least four petroleum systems in the Jiangling-Dangyang
area of the Jianghan Basin. Eocene-Paleocene anoxic evaporitic lacustrine source …

Metabolic programs can differ substantially across genetically distinct subtypes of acute
myeloid leukemia (AML). These programs are not static entities but can change swiftly as a …

The apical sodium-dependent bile acid transporter (ASBT) transports bile salts from the
lumen of the gastrointestinal (GI) tract to the liver via the portal vein. Multiple pharmaceutical …

Targeting altered tumor cell metabolism might provide an attractive opportunity for patients
with acute myeloid leukemia (AML). An amino acid dropout screen on primary leukemic stem …

Acute myeloid leukemia remains difficult to treat due to strong genetic heterogeneity between
and within individual patients. Here, we show that Pyruvate dehydrogenase kinase 1 (…

Background Hypoxia-inducible factors (HIF)1 and 2 are transcription factors that regulate
the homeostatic response to low oxygen conditions. Since data related to the importance of …

The fms-like tyrosine kinase 3 (Flt3) is a cell surface receptor that is expressed by various
hematopoietic progenitor cells (HPC) and Flt3-activating mutations are commonly present in …

Cysteine is a nonessential amino acid required for protein synthesis, the generation of the
antioxidant glutathione, and for synthesizing the nonproteinogenic amino acid taurine. Here, …